{"id":"W2068574812","doi":"10.1083/jcb.201411047","title":"YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1","year":2015,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":288,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Stress granule; RNA-binding protein; Cell biology; Untranslated region; Poly(A)-binding protein; Ribonucleoprotein; Molecular biology; Cancer research; Messenger RNA; RNA; Translation (biology); Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009846875,0.0002808705,0.0001740293,0.0002462638,0.0001987703,0.0002752366,0.0001283005,0.000175,0.0007169897],"category_scores_gemma":[0.0001044076,0.0001210129,0.0001306485,0.000162191,0.0002957103,0.0001043897,0.0002198358,0.000317297,0.0003206716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005738619,"about_ca_system_score_gemma":0.0003713553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001924087,"about_ca_topic_score_gemma":0.002618198,"domain_scores_codex":[0.9999394,0.000009673639,0.000003636205,0.00001376636,0.00001106179,0.0000222834],"domain_scores_gemma":[0.9999245,0.000005558296,0.00003059562,0.000004441818,0.000008311255,0.00002648419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002021767,0.00001373647,0.0007653493,0.00001946239,0.00000377941,0.00005442763,0.00001278566,0.0000719242,0.9969475,0.0001319625,0.0001265204,0.001650439],"study_design_scores_gemma":[0.00005503025,0.000234587,0.05328041,0.00001498371,0.00002978988,0.0002827407,0.0000667495,0.002591826,0.9383255,0.0004291173,0.004680057,0.00000932224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936393,0.00276824,0.001777959,0.0001892622,0.00002753999,0.00001139758,0.0001951118,0.0001814702,0.001209788],"genre_scores_gemma":[0.9966201,0.0009137185,0.0007663505,0.00003810266,0.000007400372,0.00001131946,0.0001850042,0.00002892724,0.001429087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001924087,"threshold_uncertainty_score":0.004163682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01337223459397411,"score_gpt":0.2802046259187201,"score_spread":0.266832391324746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}