{"id":"W2068574812","doi":"10.1083/jcb.201411047","title":"YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1","year":2015,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":288,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Stress granule; RNA-binding protein; Cell biology; Untranslated region; Poly(A)-binding protein; Ribonucleoprotein; Molecular biology; Cancer research; Messenger RNA; RNA; Translation (biology); Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005952258,0.00006362448,0.00009228019,0.0000284919,0.00006717163,0.00001209066,0.0001264766,0.00005573521,0.000002714991],"category_scores_gemma":[0.00006973207,0.00003855808,0.00002768893,0.00003430596,0.00007347117,0.00001138238,0.00003149172,0.0001068118,6.484463e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007988573,"about_ca_system_score_gemma":0.00005453631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005827805,"about_ca_topic_score_gemma":0.000004499808,"domain_scores_codex":[0.999356,0.0001586022,0.0001945462,0.00005969623,0.00009709723,0.0001340953],"domain_scores_gemma":[0.9994785,0.00003566829,0.0001900902,0.00007317733,0.0001459412,0.00007668514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002620411,0.00001934802,0.0004869426,0.000009168878,0.00001087323,6.743612e-7,0.0001035138,0.0000342419,0.9900494,0.000007141253,0.0004790662,0.008537636],"study_design_scores_gemma":[0.0006592182,0.0006745331,0.000331178,0.00001841797,0.000007136328,0.00006418271,0.0002156869,0.0003146878,0.9938623,0.0002567459,0.003542177,0.00005369726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950384,0.002517736,0.001725889,0.0003547655,0.00003515938,0.00007449165,0.000006335451,0.000001744782,0.0002454377],"genre_scores_gemma":[0.9989961,0.000231396,0.0004788009,0.00005502252,0.00009906999,0.000001125073,0.0000269066,0.000005575591,0.00010602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008483939,"threshold_uncertainty_score":0.1572353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01337223459397411,"score_gpt":0.2802046259187201,"score_spread":0.266832391324746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}