{"id":"W2068662229","doi":"10.1371/journal.pbio.0030100","title":"The N. gonorrhoeae Type IV Pilus Stimulates Mechanosensitive Pathways and Cytoprotection through a pilT-Dependent Mechanism","year":2005,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Oregon Health and Science University","keywords":"Pilus; Biology; Mechanosensitive channels; Cell biology; Gene expression; Signal transduction; Cell; Gene; Neisseria gonorrhoeae; Microbiology; Genetics; Virulence; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001475724,0.0001631039,0.0001387537,0.00002026338,0.0002315918,0.00001904048,0.0001010063,0.0002498128,0.00001630077],"category_scores_gemma":[0.00004172662,0.0001208337,0.00005125427,0.00004967111,0.00009061765,0.000005366866,0.00006576403,0.0001275703,0.00002224639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001766651,"about_ca_system_score_gemma":0.00002724991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004261758,"about_ca_topic_score_gemma":0.0002230287,"domain_scores_codex":[0.9990761,0.0000811291,0.0001753618,0.000362529,0.00004734178,0.0002575939],"domain_scores_gemma":[0.9995441,0.00001940731,0.00006850837,0.0002331213,0.00008908032,0.0000457602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001900706,0.00003667927,0.0001161489,0.000004978843,0.0000682688,0.000001632918,0.0001319551,0.000008941027,0.993015,0.004366734,0.000008247809,0.002051336],"study_design_scores_gemma":[0.0007317511,0.001079806,0.0003970328,0.000009477882,0.00006018976,0.0000523428,0.0001595847,0.001384774,0.9579535,0.008717929,0.02915945,0.0002942031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807948,0.001516386,0.0162668,0.0003980049,0.0002345528,0.0003363097,0.00002014764,0.00003402842,0.0003989113],"genre_scores_gemma":[0.9970912,0.001316259,0.0003969305,0.0002226499,0.0003156641,0.0000233371,0.0004236781,0.00001913084,0.0001911663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03506154,"threshold_uncertainty_score":0.4927456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01597757550234661,"score_gpt":0.222699776078917,"score_spread":0.2067222005765704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}