{"id":"W2068662229","doi":"10.1371/journal.pbio.0030100","title":"The N. gonorrhoeae Type IV Pilus Stimulates Mechanosensitive Pathways and Cytoprotection through a pilT-Dependent Mechanism","year":2005,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Oregon Health and Science University","keywords":"Pilus; Biology; Mechanosensitive channels; Cell biology; Gene expression; Signal transduction; Cell; Gene; Neisseria gonorrhoeae; Microbiology; Genetics; Virulence; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009932676,0.0002736001,0.0001297273,0.0001291223,0.00007823701,0.0001800551,0.00006077211,0.000142808,0.0009020526],"category_scores_gemma":[0.000163497,0.00006784318,0.0001609583,0.00006436434,0.0001611378,0.0001119639,0.0001852164,0.0002595628,0.0002021289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000174204,"about_ca_system_score_gemma":0.00009673941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002249605,"about_ca_topic_score_gemma":0.0003985205,"domain_scores_codex":[0.9998937,0.00002341661,0.000005477175,0.00001125773,0.00003517885,0.000030948],"domain_scores_gemma":[0.9999093,0.00002865236,0.00001870557,0.00001265074,0.00001283506,0.00001777825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004954908,0.000007109307,0.0001275842,0.0000163663,0.000001148055,0.00002293081,0.000004958956,0.00002188247,0.9989604,0.00002046291,0.000008785297,0.0007588373],"study_design_scores_gemma":[0.00001856314,0.0004028196,0.01067202,0.000006397018,0.000005434331,0.0002181066,0.0000371127,0.0006646064,0.9867995,0.0001072253,0.001064947,0.000003301437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969664,0.000705732,0.0009805587,0.00008548755,0.00001406261,0.00001437305,0.00009561716,0.00002641133,0.001111345],"genre_scores_gemma":[0.9977432,0.0003768468,0.0009920918,0.00004592676,0.000005967943,0.00001628,0.0001186738,0.000004923955,0.000696095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009020526,"threshold_uncertainty_score":0.003017664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01597757550234661,"score_gpt":0.222699776078917,"score_spread":0.2067222005765704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}