{"id":"W2068684244","doi":"10.1371/journal.pone.0029597","title":"Capture of Neuroepithelial-Like Stem Cells from Pluripotent Stem Cells Provides a Versatile System for In Vitro Production of Human Neurons","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":359,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Technion-Israel Institute of Technology; Vetenskapsrådet; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft; European Commission; National Institute for Health and Care Research; Medical Research Council; Stem Cell Network; Wellcome Trust","keywords":"Neuroepithelial cell; Induced pluripotent stem cell; Embryonic stem cell; Biology; Stem cell; Neural stem cell; Neurosphere; Cell biology; Neuroscience; Embryoid body; Adult stem cell; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003122209,0.0003724663,0.0002789824,0.0003569956,0.000329288,0.0004653874,0.0002692796,0.0003472351,0.002071978],"category_scores_gemma":[0.0001962266,0.0002052678,0.0002703278,0.0002078151,0.0003080713,0.0002549432,0.0005889427,0.0004308235,0.001402851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001586234,"about_ca_system_score_gemma":0.0002479422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004152317,"about_ca_topic_score_gemma":0.001219686,"domain_scores_codex":[0.9997821,0.00002866145,0.00002852685,0.00006039513,0.00008058957,0.0000197696],"domain_scores_gemma":[0.9998688,0.00004014184,0.00002384787,0.00003070039,0.00002019381,0.00001641648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001456179,0.000008308389,0.0003733308,0.00003162962,0.000003595737,0.00007797179,0.00003804632,0.0000770066,0.9945629,0.000321133,0.00009144202,0.004400116],"study_design_scores_gemma":[0.000006586675,0.00007929979,0.002923595,0.00001454101,0.00001580156,0.0005805062,0.00004374959,0.0006208161,0.9818009,0.0002036089,0.01370056,0.00001009098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6871906,0.00549959,0.2850709,0.0005164241,0.0002477712,0.0006549446,0.003241784,0.0008048791,0.01677311],"genre_scores_gemma":[0.8150162,0.004469654,0.1547973,0.0003398978,0.0000984556,0.000604942,0.007370859,0.0002750802,0.01702765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002071978,"threshold_uncertainty_score":0.006931424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03249270380385714,"score_gpt":0.2335147459544078,"score_spread":0.2010220421505507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}