{"id":"W2068700927","doi":"10.1038/nrg2481","title":"Plasma lipoproteins: genetic influences and clinical implications","year":2009,"lang":"en","type":"review","venue":"Nature Reviews Genetics","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":465,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"","keywords":"Biology; Plasma lipoprotein; Computational biology; Genetic architecture; Disease; Genome-wide association study; Genetics; Genetic association; Lipoprotein; Genetic variants; Whole genome sequencing; Bioinformatics; Genome; Evolutionary biology; Gene; Quantitative trait locus; Genotype; Internal medicine; Medicine; Cholesterol; Single-nucleotide polymorphism; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001133185,0.00128734,0.002067376,0.002082581,0.0002711608,0.001274381,0.001183175,0.001841781,0.002535029],"category_scores_gemma":[0.00173185,0.0004111622,0.000461564,0.002827969,0.0009512763,0.00164756,0.001107857,0.002261568,0.001647898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007163867,"about_ca_system_score_gemma":0.001241632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001220447,"about_ca_topic_score_gemma":0.002384707,"domain_scores_codex":[0.9997262,0.00005751334,0.00004286498,0.0000550168,0.00009621793,0.00002208309],"domain_scores_gemma":[0.9990354,0.0005546618,0.00009745309,0.00002556436,0.00021651,0.00007048187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001315584,0.00004215001,0.0004991944,0.007491849,0.000133653,0.0005243786,0.00006178863,0.0003167152,0.001067924,0.003046102,0.0511157,0.935569],"study_design_scores_gemma":[0.00005393964,0.00005439028,0.002210982,0.005345642,0.0002859599,0.003953036,0.0001493185,0.0001173321,0.0003712242,0.005620679,0.9817909,0.00004661511],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006135924,0.9986001,0.000101821,0.000544086,0.0002901734,0.000001329467,0.00001197835,0.00000415662,0.0003851299],"genre_scores_gemma":[0.0003711452,0.9985368,0.0001401616,0.0002898729,0.0003870229,0.00000263257,0.0000150508,9.835283e-7,0.0002563167],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002535029,"threshold_uncertainty_score":0.008480489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07697783634379876,"score_gpt":0.4441223737611,"score_spread":0.3671445374173012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}