{"id":"W2068741730","doi":"10.1093/nar/gkv286","title":"A common tRNA modification at an unusual location: the discovery of wyosine biosynthesis in mitochondria","year":2015,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research","funders":"National Institutes of Health; National Institute of General Medical Sciences; Canadian Institute for Advanced Research","keywords":"Biology; Mitochondrion; Transfer RNA; Genetics; Context (archaeology); RNA editing; Gene; Genome; Gene duplication; Mitochondrial DNA; Translation (biology); Computational biology; RNA; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001071729,0.0001675644,0.0001821273,0.0003416577,0.0002571819,0.0004478637,0.000202167,0.0005117913,0.0002714115],"category_scores_gemma":[0.0002283213,0.0001370606,0.0001909297,0.0002420599,0.0003101616,0.0006079035,0.0004367447,0.0004275615,0.0001937722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000258236,"about_ca_system_score_gemma":0.0001520236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002691849,"about_ca_topic_score_gemma":0.0004344013,"domain_scores_codex":[0.9999332,0.00000623194,0.000004409459,0.00003064051,0.00001302271,0.00001251396],"domain_scores_gemma":[0.9998717,0.00001780329,0.00004375303,0.00002383473,0.00001627798,0.00002656784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006819018,0.000004348328,0.001989356,0.00005634181,0.000007875999,0.0007048647,0.00006763894,0.00006479092,0.9920564,0.0007263073,0.0000243545,0.004229422],"study_design_scores_gemma":[0.00001031163,0.0002871499,0.02469171,0.00003060672,0.0000527889,0.006741881,0.0002406492,0.001306248,0.9535464,0.0017926,0.01126765,0.00003205719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823548,0.003603835,0.01224609,0.000225936,0.0000363167,0.000008923545,0.0001848995,0.00007684925,0.001262261],"genre_scores_gemma":[0.9915108,0.001547438,0.005906442,0.00004507238,0.00002946828,0.00000386557,0.0001513047,0.00001577975,0.0007898136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005117913,"threshold_uncertainty_score":0.001873672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08213750688757948,"score_gpt":0.3562563994563308,"score_spread":0.2741188925687513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}