{"id":"W2068804121","doi":"10.1371/journal.pone.0105713","title":"TLR Ligands Induce Antiviral Responses in Chicken Macrophages","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Biotechnology and Biological Sciences Research Council; Poultry Industry Council; Agriculture and Agri-Food Canada; Canadian Poultry Research Council","keywords":"TLR2; Biology; Interferon; Pattern recognition receptor; Innate immune system; CpG Oligodeoxynucleotide; Viral replication; Virology; Macrophage; Immunity; Toll-like receptor; Virus; Receptor; TLR9; Microbiology; Influenza A virus; Immune system; Immunology; Gene; Gene expression; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004667423,0.0001210556,0.0002522381,0.00019323,0.00008914481,0.0000148455,0.0001521457,0.0002064672,0.0002203852],"category_scores_gemma":[0.0004232407,0.0001130685,0.00003695899,0.0001455008,0.00008697667,0.000163223,0.0000583743,0.0002753627,0.001243774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002023691,"about_ca_system_score_gemma":0.00003297489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002987679,"about_ca_topic_score_gemma":0.00000858781,"domain_scores_codex":[0.9989468,0.0003113209,0.0002452506,0.0001853071,0.00004135816,0.0002699539],"domain_scores_gemma":[0.9994162,0.0002178558,0.00007273147,0.0002477584,0.00003645819,0.000008960025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000606527,0.0003584633,0.005164983,0.00002100713,0.00008328534,0.000003628932,0.0003928342,2.37432e-7,0.9906947,0.0002559639,0.0003205634,0.002097791],"study_design_scores_gemma":[0.0009560073,0.0002071234,0.05868985,0.0001082402,0.00002475075,0.000004227297,0.00003833431,0.000009269837,0.9365014,0.00007315185,0.003254107,0.0001335023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950523,0.001610853,0.000007715301,0.0007243585,0.00008982075,0.0001450441,0.000003576009,0.00006425421,0.002302083],"genre_scores_gemma":[0.9909164,0.0002211887,0.00004849691,0.0002367599,0.00004172256,0.00001859164,0.00003984902,0.00001397634,0.008462959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05419328,"threshold_uncertainty_score":0.9995339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02345689052316114,"score_gpt":0.226271725091809,"score_spread":0.2028148345686479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}