{"id":"W2068823337","doi":"10.1016/j.placenta.2012.08.004","title":"The endogenous retroviral envelope protein syncytin-1 inhibits LPS/PHA-stimulated cytokine responses in human blood and is sorted into placental exosomes","year":2012,"lang":"en","type":"article","venue":"Placenta","topic":"COVID-19 Impact on Reproduction","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal","funders":"Australian Government","keywords":"Microvesicles; Biology; Chemokine; Ectodomain; CXCL10; Cell biology; Immune system; Cytokine; Blot; Trophoblast; Western blot; Immunology; Placenta; microRNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001023644,0.0003540315,0.0004153105,0.0002997547,0.0003820594,0.00006741314,0.0001461251,0.0001679518,0.0001233957],"category_scores_gemma":[0.001239025,0.0002751169,0.00007467187,0.0004836294,0.000214171,0.0003058947,0.0001929383,0.0004787852,0.00003852687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004129105,"about_ca_system_score_gemma":0.0001918915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007034043,"about_ca_topic_score_gemma":0.0001146928,"domain_scores_codex":[0.9973621,0.0002606263,0.0005628497,0.0005365181,0.000510637,0.0007672065],"domain_scores_gemma":[0.9985417,0.0002416473,0.0001934599,0.0006354718,0.00007646577,0.0003112954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002675827,0.0005834073,0.3591195,0.0001263096,0.0001188888,0.00006659573,0.002933493,0.000001633174,0.6326006,0.00004361328,0.0002724373,0.001457696],"study_design_scores_gemma":[0.009490362,0.0009615409,0.2768574,0.0003340102,0.0002391375,0.0009882634,0.0008837128,0.00007499343,0.7048045,0.00007657088,0.004781625,0.0005078681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933897,0.001534378,0.000003583049,0.002564051,0.0001713796,0.001840174,0.00002546821,0.0001593498,0.0003118932],"genre_scores_gemma":[0.9968356,0.000102276,0.0001313934,0.0004644076,0.0002675676,0.00007070493,0.00005452739,0.00006273952,0.002010821],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08226211,"threshold_uncertainty_score":0.9999701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0386151274400775,"score_gpt":0.309915657852946,"score_spread":0.2713005304128685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}