{"id":"W2068829341","doi":"10.2174/1567201043479993","title":"Biphasic Lipid Vesicles (Biphasix™) Enhance the Adjuvanticity of CpG Oligonucleotides Following Systemic and Mucosal Administration","year":2004,"lang":"en","type":"article","venue":"Current Drug Delivery","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Immunoadjuvant; Adjuvant; CpG Oligodeoxynucleotide; Immunization; Immune system; Antigen; Pharmacology; CpG site; Immunology; Systemic administration; Chemistry; Antibody; Medicine; Biology; In vivo; Biochemistry; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002714386,0.0004004009,0.0002088299,0.0002733675,0.000075114,0.0002659253,0.0001566791,0.000359668,0.000819995],"category_scores_gemma":[0.0001839485,0.0001653422,0.0001790507,0.0001193272,0.0001400173,0.0002658993,0.0002482131,0.0003520979,0.0003802407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002707101,"about_ca_system_score_gemma":0.0001781298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000348812,"about_ca_topic_score_gemma":0.0006088745,"domain_scores_codex":[0.9998595,0.0000364602,0.00001146893,0.0000203016,0.00004160385,0.00003074467],"domain_scores_gemma":[0.9999104,0.00001941406,0.00003049554,0.000004977642,0.00001521479,0.00001941732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004177516,0.000008999358,0.00002624036,0.00002334138,0.000002129049,0.00000886867,0.000002491828,0.00003808067,0.9986395,0.00005268766,0.00001364072,0.001142183],"study_design_scores_gemma":[0.00001583597,0.0002688547,0.0003892859,0.000006296932,0.0000108557,0.00006853815,0.000003749185,0.0004680804,0.9971465,0.00003673436,0.001582772,0.000002523556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9703142,0.005452903,0.02117431,0.0002210105,0.00007552533,0.0001713958,0.000310744,0.000151598,0.002128239],"genre_scores_gemma":[0.9780279,0.002745422,0.01444806,0.0001017015,0.00001966642,0.00009377889,0.0003490267,0.00002830885,0.004185996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000819995,"threshold_uncertainty_score":0.002743125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01554648325270684,"score_gpt":0.2781417342944685,"score_spread":0.2625952510417616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}