{"id":"W2068829341","doi":"10.2174/1567201043479993","title":"Biphasic Lipid Vesicles (Biphasix™) Enhance the Adjuvanticity of CpG Oligonucleotides Following Systemic and Mucosal Administration","year":2004,"lang":"en","type":"article","venue":"Current Drug Delivery","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Immunoadjuvant; Adjuvant; CpG Oligodeoxynucleotide; Immunization; Immune system; Antigen; Pharmacology; CpG site; Immunology; Systemic administration; Chemistry; Antibody; Medicine; Biology; In vivo; Biochemistry; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002287072,0.000215997,0.0002235373,0.00005272705,0.0001596282,0.00004607908,0.0002735239,0.00007915148,0.00000530219],"category_scores_gemma":[0.00006043926,0.0001746608,0.0001731746,0.0001033711,0.0001483688,0.00002245156,0.0001214833,0.0001278727,0.00001866245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002135783,"about_ca_system_score_gemma":0.0001501592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005370686,"about_ca_topic_score_gemma":0.0001383937,"domain_scores_codex":[0.9987191,0.0000716638,0.0003703196,0.0003844984,0.0001822978,0.0002720992],"domain_scores_gemma":[0.9992462,0.00002933785,0.0001685308,0.0003681768,0.0001082334,0.00007945687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001431374,0.0001363349,0.004526193,0.0001677696,0.0001146923,0.00000396549,0.0004189875,0.0001127943,0.9702551,0.0001126073,0.0008788548,0.02312956],"study_design_scores_gemma":[0.0008820583,0.0002684499,0.004426927,0.0005041361,0.000143295,0.00005094982,0.0006280608,0.00004421488,0.9901896,0.0002221552,0.002232644,0.0004075279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859498,0.01182157,0.001120698,0.0001085686,0.0006664288,0.0002285424,0.0000314732,0.00001800769,0.00005492588],"genre_scores_gemma":[0.9970402,0.002337076,0.0001160553,0.00005837343,0.0002919767,0.00002761861,0.00006965541,0.00001796613,0.00004112148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02272203,"threshold_uncertainty_score":0.7122463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01554648325270684,"score_gpt":0.2781417342944685,"score_spread":0.2625952510417616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}