{"id":"W2068930712","doi":"10.1016/s0165-6147(02)02086-2","title":"A ‘crash’ course on psychostimulant withdrawal as a model of depression","year":2002,"lang":"en","type":"review","venue":"Trends in Pharmacological Sciences","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":155,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute on Drug Abuse; National Institute of Mental Health","keywords":"Neurochemical; Antidepressant; Psychology; Drug withdrawal; Psychological dependence; Depression (economics); Addiction; Psychiatry; Drug; Neuroscience; Medicine; Anxiety","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001635073,0.0004484158,0.001132061,0.0004798321,0.0001821024,0.00005272542,0.001354935,0.0002539608,0.001760452],"category_scores_gemma":[0.0001886102,0.0002594479,0.0003591396,0.001823328,0.000836035,0.0001032588,0.0002039988,0.0005679192,0.00008838034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005986357,"about_ca_system_score_gemma":0.0001236549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001097604,"about_ca_topic_score_gemma":0.000002620591,"domain_scores_codex":[0.99618,0.0004789735,0.000697374,0.001147674,0.0008900864,0.0006058703],"domain_scores_gemma":[0.9981782,0.0009234581,0.0004608912,0.0002354368,0.00001365822,0.0001883407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000813334,0.0006798349,0.00001740815,0.0001344419,0.000005926328,0.00010818,0.00002319018,0.00137884,0.0003454763,0.0002429344,0.0004946119,0.9964878],"study_design_scores_gemma":[0.00561286,0.008601826,0.0002814679,0.02021712,0.001747726,0.0005275505,0.00005146113,0.3193884,0.005306461,0.002366208,0.6313604,0.004538563],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00670251,0.9634254,0.00001107788,0.0000982902,0.0004768515,0.0005790984,0.0001156412,0.00009479366,0.02849632],"genre_scores_gemma":[0.04329378,0.9550554,0.0000666685,0.0002742902,0.00005522602,0.0001487016,0.00000173494,0.00001475186,0.001089418],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9919493,"threshold_uncertainty_score":0.9999858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2591397203662897,"score_gpt":0.4842506992005017,"score_spread":0.2251109788342119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}