{"id":"W2068938248","doi":"10.4161/viru.2.5.16342","title":"The M protein of group A Streptococcus is a key virulence factor and a clinically relevant strain identification marker","year":2011,"lang":"en","type":"review","venue":"Virulence","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"Abbott (Canada)","funders":"","keywords":"Biology; Virulence; Typing; Streptococcus pyogenes; Streptococcus; Group A; Outbreak; Antigen; Genotyping; Epitope; Virulence factor; Microbiology; Immunology; Virology; Genetics; Genotype; Bacteria; Medicine; Staphylococcus aureus; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004521505,0.0008601962,0.001478455,0.002514344,0.0002263592,0.0008328421,0.0006963109,0.0009481166,0.004356285],"category_scores_gemma":[0.0007149459,0.0002549683,0.000442888,0.002348081,0.0004733399,0.001034624,0.000541542,0.00121141,0.003196656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005080996,"about_ca_system_score_gemma":0.0009863555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001389837,"about_ca_topic_score_gemma":0.001716387,"domain_scores_codex":[0.9998223,0.0000276642,0.00002918792,0.00002986835,0.0000744392,0.00001651963],"domain_scores_gemma":[0.9996904,0.0001283536,0.00006492056,0.000008332488,0.00008053631,0.00002745226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007206984,0.00005958719,0.0002428153,0.01837459,0.00007996218,0.0001592915,0.00003847077,0.0001601755,0.001725256,0.001443009,0.01961161,0.9580331],"study_design_scores_gemma":[0.00001443765,0.00008011141,0.001208622,0.003412856,0.0001028337,0.001423739,0.00006528819,0.00004241413,0.0005924656,0.0007546926,0.9922866,0.00001600158],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001109043,0.9988175,0.00006610776,0.0001468423,0.00008271449,0.000003463809,0.00002536789,0.000004719976,0.000742378],"genre_scores_gemma":[0.0005481882,0.9986402,0.0001426489,0.00007699741,0.0000602967,0.000004049942,0.0000485536,9.680692e-7,0.0004780074],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004356285,"threshold_uncertainty_score":0.01457328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0724054429178853,"score_gpt":0.3698652929614616,"score_spread":0.2974598500435763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}