{"id":"W2068959905","doi":"10.1021/ol801985q","title":"Tandem Palladium-Catalyzed N,C-Coupling/Carbonylation Sequence for the Synthesis of 2-Carboxyindoles","year":2008,"lang":"en","type":"article","venue":"Organic Letters","topic":"Catalytic Cross-Coupling Reactions","field":"Chemistry","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Carbonylation; Palladium; Tandem; Catalysis; Sequence (biology); Coupling (piping); Combinatorial chemistry; Organic chemistry; Carbon monoxide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001836925,0.0001894511,0.0002452519,0.00004793109,0.0003050539,0.00002915199,0.0003633496,0.0001065382,0.0002142854],"category_scores_gemma":[0.0005809357,0.0001580436,0.0001680381,0.0002041696,0.0002966037,0.00009309226,0.00004801793,0.0001724671,0.00002113513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001981571,"about_ca_system_score_gemma":0.0001238369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000115896,"about_ca_topic_score_gemma":0.00002288053,"domain_scores_codex":[0.9987672,7.933872e-7,0.0003577651,0.0003153102,0.0002779641,0.0002809835],"domain_scores_gemma":[0.9978635,0.001123262,0.0002400933,0.0006349602,0.00008473862,0.00005342653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002068099,0.00002912332,0.003750436,0.00004789239,0.0000955267,0.000003866505,0.0002412824,0.0003066862,0.9949625,0.00002486072,0.0003527376,0.0001644084],"study_design_scores_gemma":[0.0004198458,0.00000322056,0.001806005,0.00004618439,0.0001352887,0.00004827118,0.0001179796,0.003999657,0.9930114,0.0000218403,0.0002016784,0.0001885929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964013,0.0001022839,0.001014969,0.001958352,0.0001476454,0.0001656647,0.00005005884,0.0001085192,0.00005119647],"genre_scores_gemma":[0.9992142,0.00006070017,0.0001041562,0.0001259186,0.0002734626,0.00006691318,0.00003489551,0.00005389664,0.00006580915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003692971,"threshold_uncertainty_score":0.6444829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02624582917139378,"score_gpt":0.2498917474987523,"score_spread":0.2236459183273585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}