{"id":"W2068970210","doi":"10.1093/nar/gkm578","title":"The three transfer RNAs occupying the A, P and E sites on the ribosome are involved in viral programmed -1 ribosomal frameshift","year":2007,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Biology; Ribosome; Ribosomal RNA; Transfer RNA; P-site; Genetics; Shine-Dalgarno sequence; Frameshift mutation; Ribosomal binding site; Stop codon; A-site; Mutagenesis; Eukaryotic Ribosome; Molecular biology; RNA; Mutation; Binding site; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002135446,0.0005838199,0.0003169321,0.0002301878,0.0002469417,0.0004616439,0.0002117507,0.0005559016,0.0004930727],"category_scores_gemma":[0.0003721455,0.0002091533,0.0003059743,0.0001242853,0.0005069069,0.0003248558,0.0001887827,0.0004351321,0.0003359797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002850925,"about_ca_system_score_gemma":0.000279097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002661542,"about_ca_topic_score_gemma":0.0002095618,"domain_scores_codex":[0.9997953,0.00003354584,0.00001580631,0.00006124683,0.00005611028,0.000037958],"domain_scores_gemma":[0.9997357,0.00007630382,0.0001000679,0.00002657175,0.00002052346,0.00004081846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008483197,0.00002112237,0.0006281959,0.00002468939,0.000003489859,0.0001026337,0.00001960869,0.0002314121,0.9955276,0.0005238654,0.000009731437,0.002822796],"study_design_scores_gemma":[0.00001411919,0.0002915347,0.004797434,0.00000721874,0.000008775171,0.0004554362,0.00004788082,0.0008905844,0.9921091,0.0003863313,0.0009802144,0.00001139778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904292,0.001411666,0.007090245,0.00006079307,0.0000178573,0.00002505764,0.00005027413,0.00008402479,0.000830944],"genre_scores_gemma":[0.9951757,0.0003882333,0.003848659,0.00001824823,0.000004918887,0.00001708465,0.00005585059,0.00001004991,0.0004812751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005838199,"threshold_uncertainty_score":0.00206846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04986435531252009,"score_gpt":0.3165023488357928,"score_spread":0.2666379935232727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}