{"id":"W2068970210","doi":"10.1093/nar/gkm578","title":"The three transfer RNAs occupying the A, P and E sites on the ribosome are involved in viral programmed -1 ribosomal frameshift","year":2007,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Biology; Ribosome; Ribosomal RNA; Transfer RNA; P-site; Genetics; Shine-Dalgarno sequence; Frameshift mutation; Ribosomal binding site; Stop codon; A-site; Mutagenesis; Eukaryotic Ribosome; Molecular biology; RNA; Mutation; Binding site; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004563229,0.0001892902,0.0001430197,0.00006536923,0.0008749209,0.0002173318,0.0007638732,0.0002481999,0.00002985265],"category_scores_gemma":[0.0006207995,0.00009216993,0.00008872611,0.0002671911,0.0006205324,0.00000774554,0.000216368,0.0006792345,0.00002261025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002659419,"about_ca_system_score_gemma":0.00005711998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006674306,"about_ca_topic_score_gemma":0.001285389,"domain_scores_codex":[0.9974713,0.0004795619,0.0002493628,0.0004055554,0.000599918,0.0007942572],"domain_scores_gemma":[0.9984781,0.0006130358,0.00003341912,0.0006662153,0.0001083229,0.0001009615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008991332,0.0001148636,0.02733666,0.00002341916,0.00007166022,0.00002505347,0.0005104381,0.00000188779,0.9057406,0.00975033,0.000629549,0.05489647],"study_design_scores_gemma":[0.001017499,0.001073016,0.08033099,0.0000986048,0.00001287554,0.0000109845,0.00375287,0.0001456659,0.8498848,0.01072181,0.05256344,0.0003874399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914243,0.001312891,0.0003529416,0.004965904,0.00005419993,0.0009465668,0.000007076173,0.00001333739,0.00092278],"genre_scores_gemma":[0.9986764,0.0002685836,0.00009374961,0.0003589083,0.0002293957,0.0001445287,0.000006307899,0.00003316345,0.0001889518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05585572,"threshold_uncertainty_score":0.6729273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04986435531252009,"score_gpt":0.3165023488357928,"score_spread":0.2666379935232727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}