{"id":"W2068977602","doi":"10.1002/eji.200636830","title":"Syk‐dependent ERK activation regulates IL‐2 and IL‐10 production by DC stimulated with zymosan","year":2007,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":159,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Syk; Zymosan; TLR2; MAPK/ERK pathway; Biology; Cell biology; Receptor; Signal transduction; TLR4; Biochemistry; Tyrosine kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001019276,0.0002329206,0.0001716359,0.0001436394,0.0001448736,0.0003733811,0.0001020616,0.0001325352,0.001466093],"category_scores_gemma":[0.0001133397,0.0001233715,0.0001707443,0.0001019787,0.0002217369,0.0002057775,0.0002011911,0.0004775581,0.0005890285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003165054,"about_ca_system_score_gemma":0.0001908184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003211143,"about_ca_topic_score_gemma":0.0005974925,"domain_scores_codex":[0.999897,0.00001668664,0.000007863814,0.00001327893,0.00001872097,0.00004644753],"domain_scores_gemma":[0.99993,0.0000126863,0.00001431011,0.00000788008,0.000008639936,0.00002654756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003824934,0.00003922466,0.0002579475,0.00002474555,0.000002007767,0.00004981786,0.00001038845,0.00006569389,0.9984059,0.0001082887,0.00004909118,0.0006043582],"study_design_scores_gemma":[0.00004444766,0.0001135606,0.01362071,0.000008452628,0.00000953273,0.0001607135,0.00005296796,0.002644296,0.9818693,0.0001186995,0.00135223,0.000005138698],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970824,0.0006240783,0.0006905655,0.00007771834,0.0000233121,0.00001050641,0.0002160511,0.00002072122,0.001254633],"genre_scores_gemma":[0.9965631,0.000578548,0.0006864775,0.00002874975,0.00001073594,0.0000203103,0.0003256455,0.00001050438,0.001775927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001466093,"threshold_uncertainty_score":0.004904568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008099662302264348,"score_gpt":0.2016409333916586,"score_spread":0.1935412710893943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}