{"id":"W2068977602","doi":"10.1002/eji.200636830","title":"Syk‐dependent ERK activation regulates IL‐2 and IL‐10 production by DC stimulated with zymosan","year":2007,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":159,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Syk; Zymosan; TLR2; MAPK/ERK pathway; Biology; Cell biology; Receptor; Signal transduction; TLR4; Biochemistry; Tyrosine kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001450714,0.0003397372,0.0005109961,0.0003598822,0.0002962863,0.00002784838,0.0003682408,0.0002277415,0.0003113514],"category_scores_gemma":[0.0001722713,0.000262009,0.00008448903,0.000232439,0.0006880437,0.0003457969,0.0001271722,0.0009460626,0.0002534908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007759958,"about_ca_system_score_gemma":0.00006017138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001768455,"about_ca_topic_score_gemma":0.000004406347,"domain_scores_codex":[0.9972121,0.0008661414,0.0008789077,0.0003905009,0.00008088965,0.0005714923],"domain_scores_gemma":[0.9981663,0.0001677487,0.0008990239,0.0003587583,0.0003630726,0.00004504863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002933763,0.0002680471,0.0002406076,0.00001027051,0.0007305244,0.0001115126,0.000439096,0.0000219327,0.9788001,0.0001042862,0.003178378,0.01316146],"study_design_scores_gemma":[0.003978633,0.003290469,0.009005274,0.000103076,0.0001267556,0.00436843,0.0006934824,7.420139e-7,0.8930408,0.00005658446,0.0849993,0.0003364762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898422,0.005730342,0.0009909165,0.0009657383,0.00115046,0.0001994466,0.00000816756,0.00007140235,0.001041339],"genre_scores_gemma":[0.9923584,0.0004522389,0.000236362,0.0001177996,0.0001130274,0.000001040764,0.00007075353,0.0000558621,0.006594523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08575935,"threshold_uncertainty_score":0.9999832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008099662302264348,"score_gpt":0.2016409333916586,"score_spread":0.1935412710893943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}