{"id":"W2069003092","doi":"10.1007/s11095-009-9916-0","title":"Composite Hydrogel Formulations of Stratifin to Control MMP-1 Expression in Dermal Fibroblasts","year":2009,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Biological Activity of Diterpenoids and Biflavonoids","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Matrix metalloproteinase; Fibroblast; Biomedical engineering; Pharmaceutical technology; Composite number; Tissue engineering; Chemistry; Medicine; Cell biology; Surgery; Materials science; Biology; Internal medicine; In vitro; Biochemistry; Composite material; Chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002165825,0.0002239641,0.0001570481,0.000219118,0.00009939943,0.0001822258,0.0001217922,0.0001781113,0.001122158],"category_scores_gemma":[0.0001402347,0.00008101861,0.0001445052,0.0001667655,0.00009195118,0.0002005702,0.00008641036,0.0002567436,0.0001106285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002586613,"about_ca_system_score_gemma":0.0001452688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000604614,"about_ca_topic_score_gemma":0.001434432,"domain_scores_codex":[0.9999231,0.000009228943,0.00000789668,0.00001903998,0.00001821949,0.00002253532],"domain_scores_gemma":[0.9999278,0.00002582349,0.00001559248,0.000005584461,0.00000943747,0.00001580666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007005048,0.0000182835,0.00003097209,0.00003345296,0.000002696241,0.00001713367,0.000009677403,0.00007739984,0.998053,0.00005646085,0.00002213782,0.001608715],"study_design_scores_gemma":[0.00001040499,0.0001215458,0.0002984394,0.000002755836,0.000006800235,0.00002101002,0.000004300323,0.0002707445,0.9985712,0.000008956123,0.0006824664,0.00000152932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987664,0.002906087,0.006914908,0.00007432971,0.00006658503,0.00005199255,0.0002418189,0.00005925867,0.002020809],"genre_scores_gemma":[0.992516,0.001043991,0.004341647,0.00003798181,0.00001708815,0.00003284978,0.000146394,0.00001164847,0.001852496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001122158,"threshold_uncertainty_score":0.00375396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07671961905611405,"score_gpt":0.4326419940439274,"score_spread":0.3559223749878133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}