{"id":"W2069072790","doi":"10.1371/journal.pone.0005409","title":"A Vault Nanoparticle Vaccine Induces Protective Mucosal Immunity","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"UCLA AIDS Institute; University of California, Irvine; National Institute of Allergy and Infectious Diseases; British Columbia Centre for Disease Control; National Institutes of Health; National Science Foundation","keywords":"Immunity; Vault (architecture); Immunization; Immune system; Immunology; Vaccination; Microbiology; Biology; Virology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001425037,0.0003319296,0.0002600047,0.0001716957,0.0001116414,0.000269053,0.000162205,0.0005901817,0.001171829],"category_scores_gemma":[0.0002207823,0.0001185531,0.0002309262,0.00006317634,0.0002787423,0.0002309921,0.0002535931,0.0005296837,0.0003261776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003347751,"about_ca_system_score_gemma":0.0001867435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001843209,"about_ca_topic_score_gemma":0.0002949895,"domain_scores_codex":[0.9998748,0.00001852781,0.000007882449,0.00002983399,0.00003700602,0.00003200702],"domain_scores_gemma":[0.9998642,0.00003309684,0.00003185518,0.00001557886,0.00002868278,0.00002656153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009363866,0.00003480414,0.0001261066,0.00006154416,0.000006099221,0.00004255809,0.00001099493,0.0001224824,0.99593,0.00007788983,0.00007704541,0.00341677],"study_design_scores_gemma":[0.00002762473,0.0009957437,0.001264691,0.00001197016,0.00001615207,0.0003374715,0.00001512439,0.001043666,0.993707,0.00005887585,0.002517826,0.000003950384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852556,0.002832054,0.009142275,0.0003259721,0.0001424122,0.00006585204,0.0001151162,0.0002851415,0.001835574],"genre_scores_gemma":[0.9901485,0.000643305,0.005884113,0.0001456939,0.00002738732,0.00003700545,0.0002080121,0.00002929618,0.002876618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001171829,"threshold_uncertainty_score":0.003920138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05254126609781863,"score_gpt":0.2828832526248904,"score_spread":0.2303419865270718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}