{"id":"W2069075549","doi":"10.3171/2014.9.focus14502","title":"Long-term therapy with temozolomide is a feasible option for newly diagnosed glioblastoma: a single-institution experience with as many as 101 temozolomide cycles","year":2014,"lang":"en","type":"article","venue":"Neurosurgical FOCUS","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cytodiagnostics (Canada)","funders":"","keywords":"Temozolomide; Medicine; Concomitant; Glioblastoma; Retrospective cohort study; Surgery; Internal medicine; Progression-free survival; Chemotherapy; Adjuvant therapy; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001194409,0.0004832025,0.000632202,0.0001783051,0.0002849077,0.000147206,0.0001629837,0.0001732471,0.00009634528],"category_scores_gemma":[0.0001293894,0.0003110202,0.0002101375,0.000386293,0.0002893177,0.000250888,0.00003634582,0.0001883582,0.00009505828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001717737,"about_ca_system_score_gemma":0.00009904795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001514993,"about_ca_topic_score_gemma":0.00007893176,"domain_scores_codex":[0.9974257,0.0000865782,0.0004021648,0.0008936659,0.0005902869,0.0006015743],"domain_scores_gemma":[0.998281,0.0003490197,0.0002043479,0.0005831987,0.0001701203,0.0004123152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.06162329,0.01552853,0.646345,0.0003171297,0.0006519778,0.01036541,0.001671709,0.0003471412,0.09549827,0.0104799,0.0009272727,0.1562444],"study_design_scores_gemma":[0.063903,0.05394571,0.2851878,0.001085747,0.0005292982,0.005471953,0.0001726003,0.001072193,0.5726304,0.0005275971,0.0141659,0.001307747],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924569,0.0002944308,0.001204488,0.002253902,0.0001387707,0.001935995,0.00001137076,0.0002293043,0.001474872],"genre_scores_gemma":[0.996711,0.0002035766,0.0005527466,0.001129123,0.0002054609,0.0009215369,0.00001753341,0.00007530957,0.0001837611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4771321,"threshold_uncertainty_score":0.9999342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02203038655277815,"score_gpt":0.284808193154466,"score_spread":0.2627778066016879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}