{"id":"W2069102710","doi":"10.1186/1472-6750-8-59","title":"Detection of N-acyl homoserine lactones using a traI-luxCDABE -based biosensor as a high-throughput screening tool","year":2008,"lang":"en","type":"article","venue":"BMC Biotechnology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency; University of Calgary","funders":"","keywords":"Burkholderia cenocepacia; Bioreporter; Biology; Quorum sensing; Pseudomonas aeruginosa; Biofilm; Microbiology; High-throughput screening; Homoserine; Reporter gene; Enrichment culture; Bacteria; Burkholderia; Biochemistry; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009197679,0.000826883,0.0007444559,0.0006375241,0.0002638655,0.0005750114,0.0007029286,0.0007954536,0.0007000307],"category_scores_gemma":[0.0005587605,0.0002720599,0.0004896204,0.0004973907,0.0003049969,0.000480876,0.0006283069,0.0009132352,0.0007142152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003845684,"about_ca_system_score_gemma":0.000271625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005144667,"about_ca_topic_score_gemma":0.0008099198,"domain_scores_codex":[0.9990216,0.0002596481,0.00005254016,0.0001377673,0.0004549607,0.00007342812],"domain_scores_gemma":[0.9995729,0.0001480471,0.00007640812,0.00004821555,0.00009254098,0.00006184338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001884417,0.0000297459,0.0001478324,0.00003806928,0.000005335898,0.00001640494,0.000007125622,0.00008863917,0.9984485,0.00002262812,0.00004585857,0.001131043],"study_design_scores_gemma":[0.000006323194,0.0001794078,0.0008525641,0.000004747425,0.00001403899,0.0001817155,0.00001326779,0.002904007,0.9953129,0.00003017939,0.0004915499,0.000009293234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.7975454,0.002822803,0.1939243,0.0005709708,0.0001139384,0.0003044312,0.001137402,0.001791308,0.001789384],"genre_scores_gemma":[0.7728373,0.002395744,0.2187859,0.0001648502,0.00004324227,0.0004050354,0.001405426,0.00008858745,0.003873947],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.0009197679,"threshold_uncertainty_score":0.004864275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02594957631704397,"score_gpt":0.2421226145910022,"score_spread":0.2161730382739582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}