{"id":"W2069144282","doi":"10.1016/j.stem.2009.04.003","title":"TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance","year":2009,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":249,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute","keywords":"Biology; Stem cell; Premature aging; Cell biology; Immunology; Physiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002641855,0.0003191431,0.0006399759,0.0003670981,0.0002283013,0.0005635534,0.0003920937,0.0004837356,0.002288437],"category_scores_gemma":[0.0004055738,0.000137962,0.0002574251,0.0001568351,0.0003757435,0.0003531999,0.000327235,0.001066354,0.0006561499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000162772,"about_ca_system_score_gemma":0.0003073812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002016665,"about_ca_topic_score_gemma":0.0003389104,"domain_scores_codex":[0.9998431,0.00002288527,0.00002155273,0.00002959513,0.00003347023,0.00004935756],"domain_scores_gemma":[0.9996262,0.00004358255,0.0000640448,0.00006536279,0.00004248414,0.0001583157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002725,0.0003453859,0.000816447,0.0001375041,0.0000420703,0.0002894544,0.00003832612,0.0001294182,0.9672309,0.0005308488,0.0009851853,0.0267294],"study_design_scores_gemma":[0.0004875622,0.003322865,0.01042132,0.00003637156,0.0001425311,0.00109347,0.0001160223,0.001496265,0.9667558,0.001469174,0.01463791,0.00002071364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983067,0.009164204,0.003007698,0.0006959041,0.0003497364,0.00002377244,0.000307832,0.000539676,0.002844231],"genre_scores_gemma":[0.9920672,0.002028456,0.001077616,0.0001195003,0.0001449335,0.00002018684,0.0002774388,0.00005661399,0.004207988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002288437,"threshold_uncertainty_score":0.007655561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007212537887041692,"score_gpt":0.2169558755696693,"score_spread":0.2097433376826276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}