{"id":"W2069200751","doi":"10.1016/s1097-2765(03)00091-1","title":"The Paf1 Complex Is Required for Histone H3 Methylation by COMPASS and Dot1p: Linking Transcriptional Elongation to Histone Methylation","year":2003,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":713,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Cancer Institute","keywords":"Biology; Histone methylation; Histone methyltransferase; Histone code; Histone H3; Histone; EZH2; Compass; Methylation; Histone H2A; Cell biology; Genetics; DNA methylation; Nucleosome; DNA; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02069138108277099,"score_gpt":0.290317183190774,"score_spread":0.2696258021080031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."},"direct_labels":[],"classifier":{"requested":true,"available":true,"version":"metacan-v1-d91a1de5be90","frame_rows_covered":4299418,"decision_targets":["metaresearch","metaepi_narrow","metaepi_broad","bibliometrics","sts","scholarly_communication","open_science","research_integrity","randomized_trial","nonrandomized_trial","observational","systematic_review","meta_analysis","case_report","qualitative","simulation_or_modeling","bench_or_experimental","theoretical_or_conceptual","not_applicable"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame.","warning":null},"prediction":{"classifier_version":"metacan-v1-d91a1de5be90","candidate_union":["bench_or_experimental","theoretical_or_conceptual","not_applicable"],"consensus_intersection":["bench_or_experimental"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"scores":{"codex":{"metaresearch":0.000045777065690089265,"metaepi_narrow":0.000015259021896696422,"metaepi_broad":0,"bibliometrics":0,"sts":0.000030518043793392844,"scholarly_communication":0.00006103608758678569,"open_science":0.000030518043793392844,"research_integrity":0.00007629510948348211,"randomized_trial":0.00009155413138017853,"nonrandomized_trial":0,"observational":0.0003662165255207141,"systematic_review":0,"meta_analysis":0.000015259021896696422,"case_report":0.00007629510948348211,"qualitative":0.000045777065690089265,"simulation_or_modeling":0.00018310826276035706,"bench_or_experimental":0.9948882276646067,"theoretical_or_conceptual":0.014465552758068208,"not_applicable":0.0025482566567483025,"design_other":0.0072022583352407115},"gemma":{"metaresearch":0.000030518043793392844,"metaepi_narrow":0.000015259021896696422,"metaepi_broad":0,"bibliometrics":0,"sts":0.00007629510948348211,"scholarly_communication":0.000015259021896696422,"open_science":0.000045777065690089265,"research_integrity":0.00044251163500419623,"randomized_trial":0.00010681315327687495,"nonrandomized_trial":0.0001373311970702678,"observational":0.002746623941405356,"systematic_review":0,"meta_analysis":0,"case_report":0.000030518043793392844,"qualitative":0.000015259021896696422,"simulation_or_modeling":0.00019836728465705348,"bench_or_experimental":0.8689402609292745,"theoretical_or_conceptual":0.014801251239795529,"not_applicable":0.42792401007095443}},"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame."}}