{"id":"W2069271524","doi":"10.1038/icb.2010.80","title":"Lowering TCR expression on naive CD8<sup>+</sup> T cells does not affect memory T‐cell differentiation","year":2010,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; T-cell receptor; CD8; Cell biology; Biology; Interleukin 21; T cell; IL-2 receptor; Effector; Naive T cell; Immunology; Antigen; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004122583,0.0007662803,0.0009298752,0.0004157031,0.0007808596,0.00003458194,0.0007103793,0.002362767,0.001992354],"category_scores_gemma":[0.00007523635,0.0005657463,0.0002577647,0.0001549228,0.001495217,0.0001494441,0.0005072908,0.002287228,0.001703316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004485738,"about_ca_system_score_gemma":0.00007694303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000180735,"about_ca_topic_score_gemma":0.0000419505,"domain_scores_codex":[0.9959713,0.0007353025,0.000720713,0.001285708,0.00005313056,0.001233802],"domain_scores_gemma":[0.9975369,0.0008785671,0.0004198449,0.0009893383,0.0001033435,0.00007201284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001031322,0.0005914061,0.001316523,0.00004767607,0.0001846298,0.00001828657,0.0007078241,0.00001188993,0.9910176,0.0004032762,0.0004530515,0.004216486],"study_design_scores_gemma":[0.003597102,0.001183223,0.001057719,0.0000311345,0.00009570915,0.00007116583,0.0004228977,0.00001660367,0.977797,0.0003556992,0.01469869,0.0006730178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863619,0.002544483,0.0001068061,0.0002621919,0.005375567,0.0005453233,0.00008383061,0.0002726284,0.004447269],"genre_scores_gemma":[0.9904143,0.001015667,0.00009170186,0.0004444677,0.0001635653,0.0001002349,0.0003228899,0.0000642837,0.007382949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01424563,"threshold_uncertainty_score":0.9996794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005606691173225212,"score_gpt":0.2051422995209579,"score_spread":0.1995356083477327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}