{"id":"W2069271524","doi":"10.1038/icb.2010.80","title":"Lowering TCR expression on naive CD8<sup>+</sup> T cells does not affect memory T‐cell differentiation","year":2010,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; T-cell receptor; CD8; Cell biology; Biology; Interleukin 21; T cell; IL-2 receptor; Effector; Naive T cell; Immunology; Antigen; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001531334,0.0003219481,0.0003155494,0.00008756745,0.00009845402,0.0005367284,0.0002335445,0.0002769291,0.001672216],"category_scores_gemma":[0.000243653,0.0001470042,0.0001513227,0.00008840115,0.0002560841,0.0002299867,0.0001582651,0.0009826476,0.0004910565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000221458,"about_ca_system_score_gemma":0.0001392391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002727926,"about_ca_topic_score_gemma":0.0003134087,"domain_scores_codex":[0.9996915,0.00006534214,0.00003811708,0.00004608218,0.00006698744,0.0000920388],"domain_scores_gemma":[0.9996923,0.0001108307,0.00006833607,0.00004476549,0.00002901916,0.00005471261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009148302,0.00002831669,0.00006406754,0.00001094792,0.000001747394,0.00001393065,0.000005065915,0.00003087235,0.9993844,0.00002635452,0.00001239278,0.0003303897],"study_design_scores_gemma":[0.00001744747,0.0004035571,0.001016835,0.00000279098,0.00001430417,0.00007994127,0.00001053275,0.0004297738,0.997189,0.00001810914,0.0008157323,0.000001973489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974344,0.0003562403,0.000904239,0.00005922522,0.00002831335,0.00001314964,0.0001087911,0.00005070094,0.001044937],"genre_scores_gemma":[0.996781,0.0002391556,0.001164612,0.00007128932,0.00001359709,0.00002261193,0.0002344012,0.00003533731,0.001438004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001672216,"threshold_uncertainty_score":0.005594075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005606691173225212,"score_gpt":0.2051422995209579,"score_spread":0.1995356083477327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}