{"id":"W2069276819","doi":"10.1074/jbc.m010750200","title":"RANTES Activates Jak2 and Jak3 to Regulate Engagement of Multiple Signaling Pathways in T Cells","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Cancer Institute","keywords":"Phosphorylation; Tyrosine phosphorylation; Cell biology; T cell; Signal transduction; Chemokine receptor CCR5; CCL5; Biology; CCR1; Molecular biology; Chemokine; Chemokine receptor; Chemistry; Receptor; IL-2 receptor; Biochemistry; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003753866,0.0001081391,0.0003533093,0.00005777573,0.000027178,0.000008691608,0.00007050245,0.0000920682,0.0002351585],"category_scores_gemma":[0.0004428162,0.00007179169,0.0001119815,0.0001242485,0.00004428265,0.00003690793,0.00004169925,0.0003215966,0.000001166199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004021846,"about_ca_system_score_gemma":0.00002909148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006152547,"about_ca_topic_score_gemma":3.625254e-7,"domain_scores_codex":[0.9990823,0.00002920128,0.0004901416,0.0001260925,0.0001257415,0.0001465299],"domain_scores_gemma":[0.9991922,0.0002592769,0.0002145731,0.00008545549,0.0001197517,0.0001287261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005562115,0.000215072,0.01503265,0.00004420956,0.00003227073,0.0001004173,0.0001378202,0.000101234,0.9820076,0.000001475059,0.0000622221,0.001708835],"study_design_scores_gemma":[0.001005706,0.0005056933,0.006841551,0.0003966303,0.0000181074,0.0002435629,0.0004594286,0.00007957134,0.9889426,0.00005188876,0.001379947,0.00007529319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989566,0.0002212203,0.0001065272,0.0002403741,0.00004273752,0.00007650991,0.000006084497,0.00000625499,0.0003436712],"genre_scores_gemma":[0.9982896,0.0002022308,0.00122124,0.00008800264,0.0001509533,0.000001793171,0.000002567837,0.000005870792,0.00003772871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008191104,"threshold_uncertainty_score":0.292758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05462404391982776,"score_gpt":0.2809212893353285,"score_spread":0.2262972454155007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}