{"id":"W2069301738","doi":"10.1038/cgt.2009.28","title":"Lentiviruses with trastuzumab bound to their envelopes can target and kill prostate cancer cells","year":2009,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Vancouver General Hospital","funders":"Office of Defense Programs; BC Cancer Agency; Terry Fox Foundation","keywords":"LNCaP; Prostate cancer; Trastuzumab; Cancer research; Cytotoxic T cell; Luciferase; Antibody; Antigen; Monoclonal antibody; Virology; Biology; Cell culture; Cancer; Transfection; Immunology; In vitro; Breast cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002400885,0.0003058979,0.0002304812,0.0002323403,0.0001782079,0.0006543844,0.0002556486,0.0004067576,0.0007317387],"category_scores_gemma":[0.0002813195,0.0001745289,0.0002660374,0.0001593036,0.0003427256,0.0003776361,0.0002754818,0.0007808699,0.0002396677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007115643,"about_ca_system_score_gemma":0.0002722605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001278555,"about_ca_topic_score_gemma":0.001117373,"domain_scores_codex":[0.9998222,0.00002521947,0.000009580005,0.0000182501,0.00007070798,0.00005411137],"domain_scores_gemma":[0.9999055,0.00003072314,0.00002030985,0.00001693906,0.00001060412,0.00001598163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001431498,0.00003746341,0.0002725652,0.00003012398,0.00002033144,0.00007100443,0.00004209137,0.0002916987,0.9941906,0.001073864,0.0001500869,0.003676986],"study_design_scores_gemma":[0.00004365748,0.0001641791,0.001251104,0.00000633942,0.00003283663,0.0002721119,0.00002042602,0.001908775,0.9917687,0.0002021561,0.00432412,0.000005649399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855568,0.002731219,0.007979599,0.0002150579,0.0000777392,0.00004764441,0.0001466412,0.000127447,0.003117814],"genre_scores_gemma":[0.9931962,0.0007727318,0.001938327,0.00007439518,0.00001419735,0.00002384682,0.0002481029,0.00003226607,0.003699871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001278555,"threshold_uncertainty_score":0.005162776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01745088884056964,"score_gpt":0.2911360393492196,"score_spread":0.2736851505086499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}