{"id":"W2069327083","doi":"10.1016/j.leukres.2013.04.014","title":"Ectodomain shedding of CD200 from the B-CLL cell surface is regulated by ADAM28 expression","year":2013,"lang":"en","type":"article","venue":"Leukemia Research","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Ectodomain; Disintegrin; Transfection; Molecular biology; Biology; ADAM10; Metalloproteinase; Cell culture; Glycoprotein; Cell biology; Enzyme; Receptor; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.002240289,0.0003245783,0.0005926608,0.0001753862,0.0003655858,0.0001308904,0.001065114,0.0004377836,0.006277098],"category_scores_gemma":[0.0007853929,0.0002167602,0.0001956295,0.001245826,0.0007614724,0.0002416588,0.0007873871,0.001597764,0.001169312],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.01469099,"about_ca_system_score_gemma":0.007750461,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03695968,"about_ca_topic_score_gemma":0.00004232139,"domain_scores_codex":[0.993138,0.0008131232,0.0006884456,0.0008478626,0.003096025,0.001416598],"domain_scores_gemma":[0.9933986,0.003141338,0.0001394894,0.00193819,0.0008635866,0.0005187767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002978637,0.00009903067,0.000617097,0.0001227599,0.0000497464,0.00003771403,0.0008598148,0.00004230044,0.5960437,0.00001611107,0.4009249,0.0008890014],"study_design_scores_gemma":[0.0125521,0.0003975475,0.001084827,0.0005765762,0.00003018024,0.00002727222,0.001335028,0.0306483,0.9406278,0.0007246659,0.01173199,0.0002637866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821872,0.002823758,0.00007565561,0.001794804,0.00008111419,0.00167955,0.00007196293,0.00007947157,0.01120654],"genre_scores_gemma":[0.975659,0.0004518774,0.001303634,0.0002948118,0.0002207312,0.00008274085,0.0001109614,0.0001023979,0.02177381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3891929,"threshold_uncertainty_score":0.9996084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03315386894783093,"score_gpt":0.3298452281077127,"score_spread":0.2966913591598818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}