{"id":"W2069327976","doi":"10.1016/j.cell.2009.09.003","title":"Reprogramming to Pluripotency: From Frogs to Stem Cells","year":2009,"lang":"en","type":"article","venue":"Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; Reprogramming; Stem cell; Cell biology; Induced pluripotent stem cell; Evolutionary biology; Genetics; Embryonic stem cell; Cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001912246,0.0001966336,0.0001775176,0.00007366476,0.0000785649,0.00006520926,0.0004746981,0.0001506182,0.00005531551],"category_scores_gemma":[0.00001707572,0.0001982374,0.0001025456,0.0001930582,0.0000178565,0.000003275399,0.0002111671,0.0001192839,0.001038064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003130341,"about_ca_system_score_gemma":0.00005676365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006578625,"about_ca_topic_score_gemma":0.00001719004,"domain_scores_codex":[0.9981709,0.00005716579,0.0002292806,0.0007406914,0.0002731945,0.0005288103],"domain_scores_gemma":[0.9986439,0.00001294565,0.00004008264,0.0007992341,0.00008673291,0.0004171155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007252254,0.00008508163,0.00009797995,0.000006355247,0.00001006925,0.00002257936,0.0001087978,0.0001322802,0.9653592,0.000002112186,0.0146282,0.01947488],"study_design_scores_gemma":[0.0002364708,0.0003794621,0.0003835317,0.0000113863,0.000006282064,0.000001186221,0.00005293699,0.00001923924,0.7738881,0.00002878326,0.2247906,0.0002020357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876224,0.0006345481,0.003567098,0.0007832177,0.0002203814,0.0005445587,0.00003267214,0.00004109137,0.006554021],"genre_scores_gemma":[0.978471,0.00005246471,0.006195185,0.001555998,0.0003530366,0.00002490707,0.00005675438,0.00003185145,0.01325877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2101624,"threshold_uncertainty_score":0.9997398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307449727528538,"score_gpt":0.2555781537660428,"score_spread":0.2425036564907574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}