{"id":"W2069327976","doi":"10.1016/j.cell.2009.09.003","title":"Reprogramming to Pluripotency: From Frogs to Stem Cells","year":2009,"lang":"en","type":"article","venue":"Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; Reprogramming; Stem cell; Cell biology; Induced pluripotent stem cell; Evolutionary biology; Genetics; Embryonic stem cell; Cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004524053,0.0002542117,0.0004234623,0.0005102808,0.0004525645,0.000978152,0.0003990373,0.0005213659,0.002657839],"category_scores_gemma":[0.000344421,0.0002774325,0.0003427648,0.0003973616,0.001045434,0.0008703397,0.0005380585,0.001183119,0.0006479331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000629788,"about_ca_system_score_gemma":0.0003984054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001067328,"about_ca_topic_score_gemma":0.001258695,"domain_scores_codex":[0.9997954,0.00004600551,0.00001705916,0.00005027176,0.00005920033,0.00003203685],"domain_scores_gemma":[0.9998404,0.00003087513,0.00003376155,0.00003468419,0.00002315002,0.00003717159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001823143,0.00002013841,0.002473442,0.0002958679,0.00003793848,0.0003612393,0.0003819383,0.0007745973,0.9165406,0.02894265,0.0006139057,0.04937523],"study_design_scores_gemma":[0.00008647914,0.0008432329,0.01687922,0.0002368023,0.0001627448,0.003189656,0.0007577817,0.00235904,0.820419,0.01840832,0.1365655,0.00009219415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7929767,0.03135344,0.09594206,0.004094389,0.0009234758,0.0001984268,0.001723157,0.001650251,0.07113815],"genre_scores_gemma":[0.9295972,0.01370292,0.02974438,0.0005935807,0.00006897435,0.00005866961,0.0005564069,0.0001356182,0.02554223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002657839,"threshold_uncertainty_score":0.008891344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307449727528538,"score_gpt":0.2555781537660428,"score_spread":0.2425036564907574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}