{"id":"W2069336075","doi":"10.1021/ja0525298","title":"Catalytic Asymmetric Hydrogenation of <i>N</i>-Iminopyridinium Ylides:  Expedient Approach to Enantioenriched Substituted Piperidine Derivatives","year":2005,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":288,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Enantioselective synthesis; Reactivity (psychology); Piperidine; Catalysis; Pyridine; Enantiomer; Ligand (biochemistry); Combinatorial chemistry; Organic chemistry; Enantiomeric excess","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002360692,0.0004301942,0.0003067188,0.0001038686,0.0001183119,0.0001841096,0.0004205161,0.0002222074,0.001547865],"category_scores_gemma":[0.0002549014,0.0001368777,0.0001401321,0.0001178273,0.0002100346,0.0003308734,0.0002403205,0.0005357573,0.0003966449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001724094,"about_ca_system_score_gemma":0.0001621112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002599251,"about_ca_topic_score_gemma":0.000411676,"domain_scores_codex":[0.9998819,0.00002445007,0.00001148773,0.0000209731,0.00002618506,0.00003508098],"domain_scores_gemma":[0.9999346,0.00001269752,0.00002031399,0.00001238851,0.000009360376,0.00001067688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001469209,0.00005035549,0.0001523086,0.0002312819,0.000009834508,0.0003902202,0.00008716935,0.00079049,0.9843711,0.001784153,0.0002797139,0.01170648],"study_design_scores_gemma":[0.00002130229,0.0001321605,0.0001630243,0.000003210994,0.000006599764,0.0002096378,0.00001125838,0.0009241047,0.9960365,0.00007917538,0.002407093,0.000005967646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9560988,0.00247341,0.02572946,0.0004111919,0.00009949468,0.00008336934,0.0003107891,0.0002228253,0.01457066],"genre_scores_gemma":[0.9885964,0.001463305,0.007834258,0.00006352396,0.00002222449,0.00002158699,0.0001145049,0.00004582272,0.00183829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001547865,"threshold_uncertainty_score":0.005178154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01370882650215757,"score_gpt":0.249555907872833,"score_spread":0.2358470813706755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}