{"id":"W2069340479","doi":"10.1097/cad.0b013e3280262427","title":"Gene expression profiles as biomarkers for the prediction of chemotherapy drug response in human tumour cells","year":2007,"lang":"en","type":"review","venue":"Anti-Cancer Drugs","topic":"Gene expression and cancer classification","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Laurentian University; Sudbury Regional Hospital","funders":"","keywords":"Gene expression profiling; Biology; Vinca; Gene; Gene expression; Topoisomerase; Computational biology; Drug; Microarray; Microarray analysis techniques; Cancer research; Pharmacology; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008321556,0.0003505344,0.0005937663,0.0001985715,0.0001260768,0.00002196106,0.0004646907,0.0003655139,0.00003929637],"category_scores_gemma":[0.00002625853,0.0002479056,0.0003833984,0.0002748276,0.0001202455,0.000006310902,0.00007590461,0.0001656294,0.000002687882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007249609,"about_ca_system_score_gemma":0.0003921719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004950719,"about_ca_topic_score_gemma":0.000004836773,"domain_scores_codex":[0.9979559,0.0002288207,0.0006717834,0.0006165355,0.0002361686,0.0002908464],"domain_scores_gemma":[0.9985194,0.00008584675,0.0006036483,0.0006221117,0.0001093107,0.00005970209],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004514308,0.00008363638,0.0000179289,0.00131701,0.0001042645,2.840833e-7,0.0001213971,0.000006257127,0.8253995,0.000003290034,0.01136461,0.1611304],"study_design_scores_gemma":[0.0004209223,0.00005641683,0.00004669948,0.001145719,0.0000582675,7.818431e-7,0.00009307885,0.000003234644,0.4953189,0.000003820729,0.5027131,0.0001389804],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01917276,0.9775513,0.0003520513,0.0001032203,0.0004793395,0.001912299,0.0002935081,0.00001633349,0.0001191541],"genre_scores_gemma":[0.009725203,0.9865681,0.0001820414,0.00009264627,0.0003863508,0.0008174085,0.0003549019,0.00007794253,0.001795408],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4913485,"threshold_uncertainty_score":0.9999973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03234895651611599,"score_gpt":0.3474229593625183,"score_spread":0.3150740028464024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}