{"id":"W2069371977","doi":"10.1038/sj.cr.7290341","title":"Long-term modifications of blood pressure in normotensive and spontaneously hypertensive rats by gene delivery of rAAV-mediated cytochrome P450 arachidonic acid hydroxylase","year":2005,"lang":"en","type":"article","venue":"Cell Research","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Blood pressure; Arachidonic acid; Biology; Internal medicine; Endocrinology; Cytochrome P450; Kidney; Pharmacology; Enzyme; Medicine; Biochemistry; Metabolism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003415535,0.0001643046,0.000338291,0.0001950669,0.00007599033,0.000009841975,0.000265207,0.0002502383,0.00004768752],"category_scores_gemma":[0.0001217883,0.0001562279,0.00006501397,0.0002036305,0.0003787868,0.00000858407,0.0002238364,0.0003085257,0.000009530402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009583673,"about_ca_system_score_gemma":0.0001970775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006737449,"about_ca_topic_score_gemma":0.0000883344,"domain_scores_codex":[0.9982476,0.0002445864,0.0003673966,0.0004633638,0.0002677795,0.0004092914],"domain_scores_gemma":[0.9984813,0.0001232918,0.0001105994,0.000404905,0.0007213802,0.0001585697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003240907,0.0005241864,0.0005194152,0.00007583722,0.0001168261,0.000109383,0.00008547599,0.000063766,0.9961211,0.00000333789,0.001575602,0.0004809815],"study_design_scores_gemma":[0.001550778,0.0005579581,0.004202918,0.00001788321,0.0001008717,0.0001350967,0.00004750536,0.0005185353,0.9921643,0.000005918714,0.0005499715,0.0001482842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773961,0.02155913,0.000007860562,0.0002492038,0.00001752496,0.0004440668,0.0001608153,0.000004785454,0.0001604785],"genre_scores_gemma":[0.9933287,0.00543399,0.0001458824,0.0001649255,0.00006577672,0.00002951951,0.0002584294,0.00002541509,0.0005473963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01612514,"threshold_uncertainty_score":0.6370788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02081826235679105,"score_gpt":0.2924983052279793,"score_spread":0.2716800428711882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}