{"id":"W2069413969","doi":"10.1081/ncn-100002324","title":"STRUCTURAL, DYNAMIC, AND ENZYMATIC PROPERTIES OF MIXED α/β-OLIGONUCLEOTIDES CONTAINING POLARITY REVERSALS","year":2001,"lang":"en","type":"review","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"RNase P; DNA; Oligonucleotide; RNA; RNase H; Duplex (building); Enzyme; Chemistry; Polarity (international relations); Stereochemistry; Crystallography; Biochemistry; Biophysics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001339466,0.000328264,0.0003527337,0.000299069,0.00007195641,0.0002624925,0.0002595477,0.0002801525,0.0004698123],"category_scores_gemma":[0.000149188,0.0001249304,0.00008329714,0.0002596985,0.0001618304,0.0002985784,0.00008698893,0.0002055352,0.000576684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002430439,"about_ca_system_score_gemma":0.0001605183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003382818,"about_ca_topic_score_gemma":0.0003387486,"domain_scores_codex":[0.9999522,0.000006584325,0.000004740549,0.00001420139,0.00001709536,0.000005226932],"domain_scores_gemma":[0.9999622,0.00001014342,0.00001105584,0.000001930662,0.00001103925,0.000003501215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001393333,0.00005962734,0.0006087713,0.003025726,0.00002748276,0.0003039256,0.00006727985,0.0008578353,0.2336006,0.00224216,0.001772004,0.7572953],"study_design_scores_gemma":[0.00004374599,0.001185393,0.007433841,0.0005984015,0.0001995128,0.006120833,0.0001338503,0.001658836,0.4396654,0.003212797,0.5396854,0.00006199914],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03871818,0.948673,0.003267869,0.0002498569,0.0001301767,0.00001514769,0.00004510549,0.00004500674,0.008855642],"genre_scores_gemma":[0.1474415,0.8410666,0.003382744,0.0003292709,0.0001905671,0.00003876815,0.0001163246,0.000009440374,0.0074248],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0004698123,"threshold_uncertainty_score":0.001763344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06889779945427714,"score_gpt":0.337782263244615,"score_spread":0.2688844637903379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}