{"id":"W2069432272","doi":"10.1002/dvg.20658","title":"Loss of Necdin impairs myosin activation and delays cell polarization","year":2010,"lang":"en","type":"article","venue":"genesis","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; RIKEN; Canadian Institutes of Health Research; Heritage Medical Research Institute","keywords":"Cell polarity; Myosin; Cell biology; Biology; Null cell; PAX3; Neuroscience; Cell; Genetics; Cell culture; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006253058,0.000259054,0.0001134624,0.0001633544,0.00009030648,0.0001743447,0.0001479119,0.0001831955,0.001288058],"category_scores_gemma":[0.0001164489,0.0001423121,0.0001055773,0.00008382736,0.000202728,0.0001246883,0.0002472534,0.0003243363,0.0003532823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002419448,"about_ca_system_score_gemma":0.0001626834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007067568,"about_ca_topic_score_gemma":0.001329381,"domain_scores_codex":[0.9999105,0.00001258944,0.00001257327,0.00001742595,0.00002762119,0.00001936345],"domain_scores_gemma":[0.9998939,0.00002353612,0.00002617804,0.0000147598,0.00000728138,0.00003432565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004406383,0.000007940416,0.0001405784,0.00001051598,0.000001825392,0.00007782221,0.000006339345,0.00003306756,0.9989704,0.00006699724,0.00001432646,0.0006261542],"study_design_scores_gemma":[0.00001275187,0.000146019,0.006778707,0.000004778337,0.000008837193,0.0006645849,0.00002263431,0.0008427219,0.989945,0.00005888701,0.001512503,0.0000025827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975987,0.0002864904,0.0007603613,0.00004188509,0.000009603087,0.000003828882,0.0001377817,0.00002847367,0.001132866],"genre_scores_gemma":[0.9961665,0.0002966746,0.0006378404,0.0000185069,0.000001754421,0.000008571057,0.0002530118,0.00001171954,0.002605462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001288058,"threshold_uncertainty_score":0.004308999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004640102004151762,"score_gpt":0.2071564555204716,"score_spread":0.2025163535163199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}