{"id":"W2069452059","doi":"10.1006/bbrc.2001.5360","title":"Functional Abnormalities in Protein Tyrosine Phosphatase ε-Deficient Macrophages","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Medical Research Council; National Health and Medical Research Council; Medical Research Council Canada","keywords":"Lipopolysaccharide; Protein tyrosine phosphatase; Macrophage; Biology; Tumor necrosis factor alpha; Exon; Respiratory burst; Phenotype; Molecular biology; Cytokine; Tyrosine; Bone marrow; Immunology; Phosphatase; Function (biology); Gene; Cell biology; Biochemistry; In vitro; Phosphorylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004480345,0.0001548166,0.0001431325,0.00008713542,0.0002576544,0.00006645515,0.0005807797,0.0001201332,0.00003544437],"category_scores_gemma":[0.0004793198,0.0001387127,0.00005644735,0.0004601784,0.001033288,0.00001272155,0.0009286041,0.0003536947,0.00003779586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003589145,"about_ca_system_score_gemma":0.00009110491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000220243,"about_ca_topic_score_gemma":0.00002762658,"domain_scores_codex":[0.9983927,0.0001896793,0.0002400725,0.0003899759,0.0003480749,0.0004394685],"domain_scores_gemma":[0.9985105,0.00009511813,0.00003600312,0.0009868451,0.0001972913,0.0001742546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002133068,0.0005151478,0.0004131524,0.00002424007,0.00001197451,0.000004751108,0.00001232435,0.000001007922,0.9678028,0.02456794,0.004316138,0.002117275],"study_design_scores_gemma":[0.0005300168,0.0002149923,0.004531738,0.00005174227,0.000004198092,0.00001181492,0.00006802717,0.0001014885,0.9646359,0.001219097,0.02843753,0.000193456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9583591,0.03636244,0.0001188838,0.003815663,0.0000201964,0.000568923,0.00018584,0.00002510478,0.0005438502],"genre_scores_gemma":[0.9949597,0.00215275,0.0009627409,0.0001068274,0.000113832,0.0003189535,0.0007725939,0.00001586732,0.0005967212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03660061,"threshold_uncertainty_score":0.5656541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05931934000062141,"score_gpt":0.3397731279195627,"score_spread":0.2804537879189413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}