{"id":"W2069466371","doi":"10.1007/s12017-014-8295-9","title":"Rett Syndrome and MeCP2","year":2014,"lang":"en","type":"review","venue":"NeuroMolecular Medicine","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Rett syndrome; MECP2; Neurodevelopmental disorder; Autism; Neuroscience; Autism spectrum disorder; Neurology; Medicine; Intellectual disability; Bioinformatics; Psychology; Biology; Psychiatry; Genetics; Gene; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001978702,0.0005598163,0.00115701,0.0001405741,0.00007706105,0.00001717932,0.000350799,0.0003401816,0.00003324735],"category_scores_gemma":[0.0001812654,0.0004542362,0.0001999129,0.0001704471,0.0002161517,0.000001115673,0.0002924587,0.000275571,0.00003019628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008020175,"about_ca_system_score_gemma":0.00008545592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004401037,"about_ca_topic_score_gemma":0.000002336965,"domain_scores_codex":[0.997748,0.0002149958,0.0005125497,0.0009017803,0.0002716419,0.000351004],"domain_scores_gemma":[0.9988389,0.00002371201,0.0002102175,0.0006707231,0.00003633366,0.0002201309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001395256,0.00006812819,0.000005723112,0.01063103,0.000353065,0.0005622215,0.00002446585,6.484607e-7,0.008702888,0.0001227218,0.01174791,0.9677672],"study_design_scores_gemma":[0.0003404465,0.0006821599,0.00004652643,0.001596381,0.0003489423,0.001399293,0.000002844177,0.00000130409,0.00004786198,0.00002363502,0.9951026,0.0004080134],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006144722,0.9968638,0.0001537139,0.0001134711,0.0003664668,0.000491495,0.0000103864,0.00001929167,0.001366838],"genre_scores_gemma":[0.0008643317,0.9968095,0.0001020096,0.0009738003,0.00008335924,0.00005044533,0.0003945733,0.0001341014,0.0005879059],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9833547,"threshold_uncertainty_score":0.999791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01892215573312963,"score_gpt":0.2852757402469072,"score_spread":0.2663535845137776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}