{"id":"W2069482769","doi":"10.1021/bi300718f","title":"The bZIP Dimer Localizes at DNA Full-Sites Where Each Basic Region Can Alternately Translocate and Bind to Subsites at the Half-Site","year":2012,"lang":"en","type":"article","venue":"Biochemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences","keywords":"Binding site; bZIP domain; Dimer; Footprinting; Leucine zipper; DNA; DNA footprinting; Electrophoretic mobility shift assay; Chemistry; In silico; Cooperative binding; Affinities; Transcription factor; DNA-binding protein; Biophysics; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001214631,0.0003314919,0.0004132765,0.000111579,0.0003512202,0.0003122837,0.0005981797,0.0004222802,0.002610735],"category_scores_gemma":[0.0002517349,0.0002935538,0.0002768042,0.0001352321,0.0003466584,0.0005436388,0.0004337665,0.0004297747,0.0005033939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005139197,"about_ca_system_score_gemma":0.0004918383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001990381,"about_ca_topic_score_gemma":0.001865883,"domain_scores_codex":[0.9999322,0.00000829264,0.000002783258,0.00001666865,0.00002006455,0.00002011275],"domain_scores_gemma":[0.9999228,0.00001669372,0.00001945869,0.000009809082,0.0000117408,0.00001962212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007999408,0.0002300868,0.01333327,0.0002838671,0.0001485352,0.0005831861,0.0004044049,0.2198593,0.7489098,0.004909213,0.0005418527,0.009996487],"study_design_scores_gemma":[0.0002970116,0.0006121172,0.01468071,0.00002881089,0.0001051623,0.0005972847,0.0007414983,0.7412489,0.2333205,0.003459511,0.004838465,0.00007004589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900829,0.0001014938,0.008313078,0.00004170728,0.00000460615,0.00001132849,0.00006799711,0.00007902606,0.001297842],"genre_scores_gemma":[0.9941986,0.0001034675,0.004787918,0.00001946452,0.000001417653,0.00002721089,0.000180925,0.00003770206,0.0006433672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002610735,"threshold_uncertainty_score":0.008733809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00874806636424166,"score_gpt":0.2144225981503824,"score_spread":0.2056745317861407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}