{"id":"W2069512069","doi":"10.1007/s10858-013-9711-4","title":"Probing slowly exchanging protein systems via 13Cα-CEST: monitoring folding of the Im7 protein","year":2013,"lang":"en","type":"article","venue":"Journal of Biomolecular NMR","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Excited state; Protein folding; Chemical physics; Folding (DSP implementation); Observable; Relaxation (psychology); Dispersion (optics); Biological system; Atomic physics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004208263,0.0002198386,0.0002872452,0.0001144458,0.0001167866,0.00007523049,0.000503476,0.000191351,0.00000360274],"category_scores_gemma":[0.0001124593,0.0001548997,0.0002885316,0.0002342285,0.00007474426,0.00002348363,0.0001922673,0.0002264944,0.000001909428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004395341,"about_ca_system_score_gemma":0.0001192233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005701409,"about_ca_topic_score_gemma":0.000001189354,"domain_scores_codex":[0.9983209,0.000141973,0.0006064309,0.0002111967,0.0003934648,0.0003260575],"domain_scores_gemma":[0.9983435,0.000005981409,0.0007765538,0.000407976,0.0003647321,0.0001012563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002567338,0.00002742922,0.0003875957,0.0001300031,0.0001095527,0.0000125263,0.0000663472,0.0002678539,0.9962848,0.0000689743,0.00001964104,0.002599578],"study_design_scores_gemma":[0.0004698274,0.0002634562,0.0002877959,0.0005942312,0.00003660622,0.0001987741,0.0001108063,0.0005615145,0.9963659,0.0002812815,0.0006308328,0.0001989929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9481031,0.002590785,0.04781327,0.0001132197,0.0003311155,0.0009308369,0.000002592569,0.000006585838,0.0001085297],"genre_scores_gemma":[0.9956452,0.00001557291,0.003619777,0.00002114321,0.0004610306,0.00004432676,0.000001866082,0.00003820308,0.0001529424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04754207,"threshold_uncertainty_score":0.6316627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00567206533780878,"score_gpt":0.2180401492925978,"score_spread":0.212368083954789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}