{"id":"W2069540396","doi":"10.1371/journal.pone.0110730","title":"Identification of Reference Proteins for Western Blot Analyses in Mouse Model Systems of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (TCDD) Toxicity","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"Academy of Finland; Canadian Institutes of Health Research; Government of Ontario; Ontario Institute for Cancer Research","keywords":"Biology; Blot; Messenger RNA; Western blot; Toxicity; Computational biology; Gene; Genetics; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002534791,0.0001004249,0.0002409606,0.00006374993,0.00002171886,0.000006146815,0.0002157594,0.0001652,9.155302e-7],"category_scores_gemma":[0.0001101933,0.00009840455,0.00005411668,0.00007367913,0.00005957394,0.000003397268,0.00004725844,0.00005402463,7.609557e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008319549,"about_ca_system_score_gemma":0.0000255366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005380276,"about_ca_topic_score_gemma":0.00007430383,"domain_scores_codex":[0.999024,0.00005210871,0.0004209886,0.0002739017,0.0001041798,0.0001247756],"domain_scores_gemma":[0.9990518,0.00001298729,0.0002568926,0.0004679602,0.0001805911,0.00002977108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003597993,0.0006267299,0.001175683,0.000165656,0.00005065473,1.959109e-8,0.00001276245,0.0004480309,0.9966093,0.000825195,0.000008867964,0.00004111905],"study_design_scores_gemma":[0.000198165,0.0002025647,0.0004625763,0.00004035143,0.00003816947,2.305926e-7,0.000007495462,0.01041806,0.9883605,0.0001597949,0.00001591567,0.00009617526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8626279,0.0001009385,0.1363686,0.0000291794,0.000003103592,0.0006595841,0.0001358079,0.00001096998,0.00006389502],"genre_scores_gemma":[0.9924622,0.0000649726,0.006512539,0.00001651143,0.0000214027,0.0004176627,0.0001560562,0.00001409184,0.000334626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1298561,"threshold_uncertainty_score":0.4012821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07813351127338528,"score_gpt":0.3133526731229008,"score_spread":0.2352191618495156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}