{"id":"W2069616965","doi":"10.1016/j.bmc.2006.05.019","title":"Short pseudopeptides containing turn scaffolds with high AT2 receptor affinity","year":2006,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Vetenskapsrådet","keywords":"Chemistry; Receptor; Turn (biochemistry); Amino acid; Stereochemistry; Affinities; Amino acid residue; Peptide; Angiotensin II; Combinatorial chemistry; Biochemistry; Peptide sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001759275,0.000508089,0.000461039,0.0001921075,0.000195649,0.000361892,0.000291833,0.0003650057,0.002032392],"category_scores_gemma":[0.0002275614,0.0002278562,0.0002708846,0.0001993448,0.0002048277,0.0004564495,0.0003543994,0.0007118057,0.0008793452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002068538,"about_ca_system_score_gemma":0.000130333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001202043,"about_ca_topic_score_gemma":0.000214506,"domain_scores_codex":[0.9998904,0.00002047383,0.000007923398,0.00001899192,0.00002300184,0.00003923323],"domain_scores_gemma":[0.9997814,0.00005743276,0.00005425265,0.00001651083,0.00002369499,0.0000666983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004831828,0.00003241494,0.00009166491,0.00007247358,0.00001239899,0.0002285535,0.00002817615,0.0005749599,0.9935968,0.0005661575,0.0001404506,0.004172725],"study_design_scores_gemma":[0.000115875,0.001381252,0.0009421385,0.000008146044,0.0000471458,0.0006415336,0.00003557164,0.001143138,0.9888809,0.0002768094,0.006503571,0.00002399982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791748,0.002370255,0.01350037,0.0001549587,0.0001801435,0.00009494305,0.0003902141,0.0002337817,0.003900495],"genre_scores_gemma":[0.9882179,0.001093566,0.006814259,0.0002512842,0.00006987492,0.00008158081,0.0007046942,0.00005225969,0.002714611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002032392,"threshold_uncertainty_score":0.006799042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006088149889649584,"score_gpt":0.2013661349247668,"score_spread":0.1952779850351172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}