{"id":"W2069662317","doi":"10.1210/en.2009-0602","title":"17β-Estradiol Accelerates Tumor Onset and Decreases Survival in a Transgenic Mouse Model of Ovarian Cancer","year":2010,"lang":"en","type":"article","venue":"Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Canadian Institutes of Health Research","keywords":"Internal medicine; Ovarian cancer; Endocrinology; Genetically modified mouse; Transgene; Cancer; Medicine; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003902276,0.00073466,0.000595939,0.001039258,0.0002714327,0.0004378452,0.0004438099,0.0008585532,0.002278376],"category_scores_gemma":[0.0002120485,0.0004498481,0.0005713437,0.0004305159,0.0003973676,0.0003727693,0.0002613612,0.001452444,0.000672054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005541452,"about_ca_system_score_gemma":0.0004217053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001008343,"about_ca_topic_score_gemma":0.001589411,"domain_scores_codex":[0.9996825,0.00004427585,0.00003790077,0.00007810775,0.00008122059,0.00007594977],"domain_scores_gemma":[0.9996027,0.00004582396,0.0001487455,0.00003802054,0.00003138701,0.0001333535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007465112,0.0003948401,0.0006027956,0.0000503056,0.00001648544,0.0001989065,0.00004642149,0.0001813412,0.9948302,0.0002717563,0.0002737697,0.002386675],"study_design_scores_gemma":[0.0009478536,0.007499663,0.01886169,0.00007003269,0.0001464295,0.002323236,0.0001655175,0.004456134,0.9459624,0.0006583676,0.01885491,0.00005383375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866806,0.003406176,0.003832503,0.0006172778,0.0002163931,0.0001432881,0.002147258,0.0005653617,0.002391172],"genre_scores_gemma":[0.9651777,0.006231874,0.00524824,0.000432586,0.0000863143,0.0004352585,0.003539556,0.0002143651,0.01863416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002278376,"threshold_uncertainty_score":0.007621944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01244693906001715,"score_gpt":0.2590772424576643,"score_spread":0.2466303033976471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}