{"id":"W2069664412","doi":"10.1016/s0006-3495(00)76288-6","title":"Block of Voltage-Dependent Calcium Channels by Aliphatic Monoamines","year":2000,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Chemistry; Stereochemistry; Farnesol; Biophysics; Calcium channel; Voltage-dependent calcium channel; Block (permutation group theory); Gene isoform; Calcium; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007319079,0.0001077361,0.0001245451,0.00002646179,0.00006929725,0.00002350159,0.0001040414,0.00008924322,0.0002009354],"category_scores_gemma":[0.00001323802,0.00008987195,0.0001171147,0.0000626802,0.00005125031,0.00000568043,0.00001747361,0.00007675219,0.00003211665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009528478,"about_ca_system_score_gemma":0.0000203386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005663366,"about_ca_topic_score_gemma":2.384286e-7,"domain_scores_codex":[0.9992689,0.0000331121,0.000216114,0.0001441671,0.0001823347,0.0001553533],"domain_scores_gemma":[0.9996069,0.000005284832,0.00008372722,0.0001171109,0.00008259773,0.0001043808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009221011,0.0001369252,0.00005199898,0.000005373997,0.00003501649,0.000001742852,0.00002141495,0.0003652123,0.985648,0.00001381958,0.008494375,0.005133919],"study_design_scores_gemma":[0.0006337442,0.000365918,0.0002866197,0.00001114613,0.00001986678,0.00006542014,0.00003185811,0.001711713,0.9688352,0.00004818658,0.02784408,0.0001462454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954721,0.00009311029,0.003284177,0.0001887515,0.0004619742,0.00006347567,0.00001339064,0.000007083014,0.0004159154],"genre_scores_gemma":[0.9929067,0.00008451383,0.00003523908,0.0001217167,0.001411267,0.000002969795,0.00002942694,0.00001312039,0.005394968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0193497,"threshold_uncertainty_score":0.3664872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01172314864198797,"score_gpt":0.2457742461894031,"score_spread":0.2340510975474151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}