{"id":"W2069721502","doi":"10.1371/journal.pone.0021648","title":"Transcriptional Priming of Salmonella Pathogenicity Island-2 Precedes Cellular Invasion","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Salmonella and Campylobacter epidemiology","field":"Agricultural and Biological Sciences","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Pathogenicity island; Biology; Salmonella enterica; Type three secretion system; Secretion; Extracellular; Intracellular; Operon; Microbiology; Intracellular parasite; Cell biology; Regulation of gene expression; Gene expression; Salmonella; Gene; Regulon; Transcriptional regulation; Virulence; Genetics; Mutant; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001817673,0.000292879,0.0003198836,0.0002832488,0.0001014766,0.0003369449,0.0001118068,0.0002996592,0.002945993],"category_scores_gemma":[0.0003928581,0.0002136397,0.0002706332,0.000128226,0.0003418534,0.0002699958,0.000543844,0.000683249,0.001142308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003807921,"about_ca_system_score_gemma":0.0002614507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005350729,"about_ca_topic_score_gemma":0.0008765912,"domain_scores_codex":[0.9997943,0.00003130823,0.000009212198,0.0000522177,0.00004655926,0.00006640916],"domain_scores_gemma":[0.9995726,0.0001239684,0.0000679033,0.00004335686,0.00008303168,0.0001091212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001807614,0.00002021996,0.0005428392,0.00002210008,0.000001108713,0.00003483073,0.00002657843,0.00002332213,0.9986015,0.00005923145,0.00003986111,0.000447821],"study_design_scores_gemma":[0.00002616908,0.0006628782,0.06757589,0.00001959465,0.000007040478,0.0001893367,0.0001854302,0.001199581,0.9281144,0.000194907,0.001811908,0.00001278732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925408,0.001066871,0.002610224,0.0001468067,0.00003635162,0.00003751313,0.0005982596,0.0001634289,0.002799639],"genre_scores_gemma":[0.994792,0.0001918431,0.001402122,0.00009231627,0.00001372723,0.00004135303,0.0008168845,0.00002543843,0.002624186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002945993,"threshold_uncertainty_score":0.00985533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1574676100466265,"score_gpt":0.2027993117448428,"score_spread":0.04533170169821635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}