{"id":"W2069727517","doi":"10.1371/journal.pone.0112965","title":"Alterations in the Expression of the NF-κB Family Member RelB as a Novel Marker of Cardiovascular Outcomes during Acute Exacerbations of Chronic Obstructive Pulmonary Disease","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Christie (Canada); McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Reseau canadien de recherche respiratoire; McGill University; GlaxoSmithKline","keywords":"RELB; COPD; Exacerbation; Medicine; Internal medicine; Inflammation; Immunology; Systemic inflammation; NFKB1; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004288036,0.0002146099,0.0002532727,0.0005331445,0.0002046101,0.00037142,0.0001684645,0.0002663001,0.0009002537],"category_scores_gemma":[0.0007392241,0.0001138078,0.0001612393,0.0003312638,0.0002706886,0.0001586268,0.0001883126,0.000362493,0.0001949622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001546203,"about_ca_system_score_gemma":0.0001025001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002240085,"about_ca_topic_score_gemma":0.0002902685,"domain_scores_codex":[0.9998339,0.00003750421,0.0000142941,0.00004595068,0.00004433584,0.00002387945],"domain_scores_gemma":[0.9993448,0.0001091505,0.0003531841,0.00002796295,0.00007431061,0.00009049635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003113966,0.0002122835,0.8941839,0.0001301196,0.00009874734,0.0005417949,0.0002550282,0.00009731863,0.09300898,0.00003576597,0.0001459102,0.008176214],"study_design_scores_gemma":[0.00002552032,0.0004406397,0.994244,0.0000105374,0.00004653678,0.001134289,0.0001281662,0.0002765842,0.003434819,0.00004846061,0.0002051497,0.000005252151],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986877,0.0008757039,0.0001709522,0.00001556655,0.000005842247,0.000007018838,0.00007705272,0.000003423332,0.000156827],"genre_scores_gemma":[0.9993311,0.000166747,0.0002302398,0.00001073859,0.00001481231,0.00001037275,0.0001169016,0.000001796019,0.0001173877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009002537,"threshold_uncertainty_score":0.003011703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02036386757459281,"score_gpt":0.2229946236901529,"score_spread":0.20263075611556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}