{"id":"W2069770612","doi":"10.1016/j.molmed.2014.12.004","title":"Nongenetic inheritance and transgenerational epigenetics","year":2014,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":241,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Transgenerational epigenetics; Epigenome; Epigenetics; Inheritance (genetic algorithm); Biology; Germline; Phenotype; Genetics; Heredity; Epigenesis; Mechanism (biology); Disease; Evolutionary biology; DNA methylation; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005449072,0.0006836337,0.0009699151,0.0009572505,0.0001841679,0.0008664771,0.0008862819,0.0008813659,0.002428888],"category_scores_gemma":[0.0004525597,0.0002207568,0.0002268975,0.001276757,0.001031463,0.001181361,0.0007414953,0.00155376,0.00107968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006153774,"about_ca_system_score_gemma":0.0007903757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007036196,"about_ca_topic_score_gemma":0.001326097,"domain_scores_codex":[0.9998724,0.00002145932,0.00001180745,0.00003253157,0.00004836925,0.00001334032],"domain_scores_gemma":[0.9998599,0.00006261122,0.00001986729,0.000009367545,0.00003231765,0.00001585509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008242443,0.0000379905,0.0003505078,0.005679296,0.00006570208,0.000430109,0.00006366011,0.0003991485,0.009230805,0.01639608,0.01712681,0.9501374],"study_design_scores_gemma":[0.00001418585,0.00003493567,0.00133925,0.001010379,0.00007048812,0.0015643,0.00006367081,0.0001165992,0.002456571,0.007767408,0.9855419,0.00002023889],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003500357,0.9959245,0.0008379472,0.0005666192,0.0003274429,0.00000301192,0.00001932284,0.0000158002,0.001955378],"genre_scores_gemma":[0.002247666,0.9949977,0.000478244,0.0003818455,0.0002870539,0.000006656735,0.00003666162,0.000003508556,0.001560629],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002428888,"threshold_uncertainty_score":0.008125424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03406404326250979,"score_gpt":0.3536463195931679,"score_spread":0.3195822763306582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}