{"id":"W2069904066","doi":"10.1053/bbmt.2002.v8.abbmt080648","title":"Chloroquine prevention of murine MHC-disparate acute graft-versus-host disease correlates with inhibition of splenic response to CpG oligodeoxynucleotides and alterations in T-cell cytokine production","year":2002,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Sanofi","keywords":"Chloroquine; Immunology; Medicine; Cytokine; CD8; Graft-versus-host disease; T cell; Cytotoxic T cell; TLR9; Major histocompatibility complex; Immune system; Biology; Transplantation; Internal medicine; Malaria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001816712,0.0005903021,0.0003805887,0.0002388032,0.0001165223,0.0001902108,0.0001973942,0.0001965839,0.0009829969],"category_scores_gemma":[0.0001675046,0.0001651038,0.0001968797,0.00009239162,0.0003113458,0.0001380804,0.0001496499,0.000530941,0.0002229822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001998886,"about_ca_system_score_gemma":0.0002022769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000554379,"about_ca_topic_score_gemma":0.001190371,"domain_scores_codex":[0.9997912,0.00004741841,0.00001845595,0.00003182319,0.00004227447,0.00006875952],"domain_scores_gemma":[0.9996947,0.0000625902,0.0001088679,0.0000218392,0.00002394323,0.00008803077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005433782,0.00009665474,0.0003637474,0.00006555098,0.000006128917,0.00004580261,0.00001705199,0.00009624717,0.997174,0.00003326959,0.0000363308,0.001521731],"study_design_scores_gemma":[0.00008620534,0.00344363,0.007762311,0.0000102418,0.00001986222,0.0002843281,0.00001397579,0.0006139911,0.9870156,0.00002051681,0.0007251016,0.000004225319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960906,0.001516445,0.001205806,0.00005218351,0.00002483739,0.00004109061,0.0001954902,0.0001041152,0.0007694596],"genre_scores_gemma":[0.9973375,0.0005706283,0.0007956192,0.00002406445,0.00001323031,0.00003164266,0.0002477126,0.00001381654,0.0009658978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009829969,"threshold_uncertainty_score":0.003288448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01364003474471252,"score_gpt":0.2462922480984981,"score_spread":0.2326522133537856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}