{"id":"W2070030853","doi":"10.1007/s10637-012-9856-0","title":"A phase I pharmacokinetic study of matuzumab in combination with paclitaxel in patients with EGFR-expressing advanced non-small cell lung cancer","year":2012,"lang":"en","type":"article","venue":"Investigational New Drugs","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Tolerability; Pharmacokinetics; Neutropenia; Paclitaxel; Lung cancer; Adverse effect; Internal medicine; Toxicity; Population; Oncology; Pharmacology; Chemotherapy; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001102334,0.001615433,0.002868091,0.0006565217,0.0006506863,0.001434463,0.0009857124,0.001287254,0.00239973],"category_scores_gemma":[0.001434582,0.000976937,0.001606109,0.0007865521,0.001142013,0.001493463,0.0003579257,0.004557115,0.0007841032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001404622,"about_ca_system_score_gemma":0.00171183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001436894,"about_ca_topic_score_gemma":0.002659354,"domain_scores_codex":[0.9994324,0.0002582595,0.00001958091,0.0001156208,0.00004844936,0.0001256952],"domain_scores_gemma":[0.9991359,0.0001759746,0.0001610337,0.00009484893,0.00003917809,0.0003930831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.726828,0.08941048,0.01155804,0.0003852732,0.001525115,0.0005714374,0.000569791,0.005521827,0.06037911,0.0004545156,0.003129037,0.09966727],"study_design_scores_gemma":[0.425868,0.5378779,0.02032195,0.00002425894,0.0007592352,0.0006041259,0.0001324436,0.004063998,0.007103363,0.0002497412,0.002919523,0.00007546265],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961235,0.0009348632,0.0005007082,0.000322007,0.00008515835,0.0006185875,0.0003673142,0.0000851633,0.0009627335],"genre_scores_gemma":[0.9953479,0.0009492563,0.00086714,0.0002913001,0.0001436897,0.000589469,0.0006593522,0.00005065354,0.001101216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002868091,"threshold_uncertainty_score":0.01019132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01128687864410548,"score_gpt":0.3151829202471673,"score_spread":0.3038960416030618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}