{"id":"W2070042847","doi":"10.1016/j.mcn.2005.07.015","title":"LNX1 is a perisynaptic Schwann cell specific E3 ubiquitin ligase that interacts with ErbB2","year":2005,"lang":"en","type":"article","venue":"Molecular and Cellular Neuroscience","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Direction de l’hospitalisation et de l’offre de Soins; March of Dimes Foundation; Alfred P. Sloan Foundation","keywords":"Neuregulin; Ubiquitin ligase; Biology; Schwann cell; Neuregulin 1; Cell biology; ErbB; Neuromuscular junction; Axon; Ubiquitin; Denervation; Immunostaining; Downregulation and upregulation; Neuroscience; Signal transduction; Anatomy; Immunology; Biochemistry; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001711624,0.0003162022,0.0002080162,0.0001455043,0.0004673564,0.0004218326,0.0004431265,0.00007568681,0.0000603582],"category_scores_gemma":[0.000046278,0.0002567568,0.00008618419,0.0004620709,0.0004861916,0.0005406516,0.0001580798,0.0003071747,0.0000785482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002601652,"about_ca_system_score_gemma":0.00005276723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000378983,"about_ca_topic_score_gemma":0.000001360255,"domain_scores_codex":[0.9973841,0.0001689739,0.0002411327,0.001076505,0.0005886114,0.0005407336],"domain_scores_gemma":[0.999014,0.00003998473,0.0001298104,0.0005118737,0.00003556694,0.000268721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003752603,0.0001256767,0.00003307973,0.00001543009,6.277529e-7,0.0005361482,0.0002636189,0.000171483,0.9967135,0.0006457802,0.0001939436,0.001263254],"study_design_scores_gemma":[0.0003754196,0.0003235118,0.00005587743,0.00002633143,0.00001228631,0.0001970546,0.00003797679,0.002975977,0.9821594,0.00004798587,0.01345467,0.0003334999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884417,0.000491834,0.006730658,0.00124079,0.0002530113,0.0003039376,0.00001047008,0.00008785103,0.002439735],"genre_scores_gemma":[0.9928918,0.00009839753,0.0004489977,0.005120118,0.00008073902,0.00001769707,0.000002229162,0.00003713075,0.001302849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01455403,"threshold_uncertainty_score":0.9999884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02054024308343936,"score_gpt":0.2247449443518784,"score_spread":0.2042047012684391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}