{"id":"W2070065173","doi":"10.1002/mrd.20688","title":"PP2Cδ (<i>Ppm1d</i>, WIP1), an endogenous inhibitor of p38 MAPK, is regulated along With <i>Trp53</i> and <i>Cdkn2a</i> following p38 MAPK inhibition during mouse preimplantation development","year":2007,"lang":"en","type":"article","venue":"Molecular Reproduction and Development","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; CDKN2A; MAPK/ERK pathway; Embryo; p38 mitogen-activated protein kinases; Kinase; Cell biology; Protein kinase A; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009494948,0.0004134924,0.0001813392,0.00029821,0.0001919599,0.000265088,0.0001778865,0.0001901495,0.001241256],"category_scores_gemma":[0.0000901009,0.0002026491,0.0002755892,0.0001444661,0.0002093078,0.000166724,0.0001528351,0.0005104739,0.0003764534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003315437,"about_ca_system_score_gemma":0.0001623661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005392886,"about_ca_topic_score_gemma":0.0007803548,"domain_scores_codex":[0.9998672,0.00001058845,0.00001343762,0.00004261939,0.00003049085,0.0000355786],"domain_scores_gemma":[0.9998758,0.00001508481,0.00005380166,0.000008307695,0.0000118825,0.000035185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004881025,0.000005810492,0.0001756816,0.00001605818,0.000001673621,0.00002773102,0.000006136231,0.00001677683,0.9992927,0.00002305259,0.00001185788,0.000373628],"study_design_scores_gemma":[0.000004950556,0.00009212925,0.006842008,0.000003420553,0.000006274709,0.000140899,0.00002027211,0.00020781,0.9918721,0.00001652606,0.0007913464,0.000002227926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932832,0.001813854,0.002808579,0.00006603692,0.00002666367,0.00002057695,0.0005616843,0.0001001056,0.001319272],"genre_scores_gemma":[0.9880134,0.001423099,0.003691437,0.00007110571,0.0000114238,0.00009083551,0.001298079,0.00004507976,0.00535554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001241256,"threshold_uncertainty_score":0.004152477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01351466492408511,"score_gpt":0.2220380636249447,"score_spread":0.2085233987008595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}