{"id":"W2070075363","doi":"10.1016/j.cub.2008.12.019","title":"Selfish DNA: Homing Endonucleases Find a Home","year":2009,"lang":"en","type":"review","venue":"Current Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Homing endonuclease; Group I catalytic intron; Biology; Intron; RNA splicing; Endonuclease; Genetics; Homing (biology); Group II intron; Computational biology; Mobile genetic elements; DNA; Gene; RNA; Plasmid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002328392,0.0005906256,0.001284664,0.0001368037,0.0001065345,0.00003427563,0.0006150248,0.0008112775,0.000103125],"category_scores_gemma":[0.0001464316,0.0004808309,0.0006847591,0.0001266798,0.0000966967,0.000002467797,0.0002227047,0.0002696991,0.0001679912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002898211,"about_ca_system_score_gemma":0.0002234072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001840304,"about_ca_topic_score_gemma":0.000001594774,"domain_scores_codex":[0.9975575,0.0003866183,0.0005522829,0.0008802427,0.00008286616,0.0005404513],"domain_scores_gemma":[0.9987012,0.00005695565,0.0003777927,0.0006703624,0.00004875909,0.0001449447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000894848,0.0000649052,0.000003358917,0.001083807,0.0000999894,0.000003541234,0.000003310774,2.278896e-8,0.001588738,0.0001952028,0.002058026,0.9948902],"study_design_scores_gemma":[0.0001648293,0.0002784982,0.00000247061,0.00152031,0.0002553967,0.00006649319,0.000002175871,1.734131e-7,0.0007035726,0.0002538197,0.9961912,0.0005610763],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001796226,0.997191,0.000269533,0.000014894,0.001202038,0.0005934704,0.0001814828,0.0000358674,0.00033205],"genre_scores_gemma":[0.0001171978,0.9965047,0.0002316025,0.00005865192,0.001305068,0.0001375745,0.001332823,0.00006094811,0.000251397],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9943291,"threshold_uncertainty_score":0.9997643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05049097222768403,"score_gpt":0.3379454002620205,"score_spread":0.2874544280343365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}