{"id":"W2070075805","doi":"10.1021/ac102614v","title":"Systematic Evaluation of Solid-Phase Microextraction Coatings for Untargeted Metabolomic Profiling of Biological Fluids by Liquid Chromatography−Mass Spectrometry","year":2011,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Chromatography; Chemistry; Solid-phase microextraction; Mass spectrometry; Metabolomics; Orbitrap; Sample preparation; Protein precipitation; Gas chromatography–mass spectrometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00117533,0.0002521003,0.000712399,0.00007889064,0.00005655166,0.000006207187,0.0002275805,0.0002669666,0.00008711419],"category_scores_gemma":[0.001035885,0.0002156161,0.0003674479,0.0002859959,0.0002057216,0.000007285131,0.00006029311,0.0001063055,8.772892e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002805043,"about_ca_system_score_gemma":0.00008011149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008436294,"about_ca_topic_score_gemma":4.44534e-7,"domain_scores_codex":[0.9980142,0.0000889868,0.0008368852,0.0004573985,0.0002922053,0.0003103168],"domain_scores_gemma":[0.9984714,0.00006870157,0.0004849555,0.0003689088,0.0005140008,0.00009204783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003878568,0.0003447572,0.0002448435,0.001629023,0.000582064,2.723165e-7,0.0000166265,0.000001551452,0.996457,0.0001291649,0.000196266,0.00001054034],"study_design_scores_gemma":[0.001275482,0.0006207093,0.00005608322,0.00009715228,0.0007590092,0.000005823373,0.0002234904,0.0009878842,0.995524,0.0002076605,0.00003022603,0.0002124087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768052,0.003453714,0.0183158,0.00001158954,0.00005561156,0.0005703397,0.0002275987,0.0000132778,0.0005468949],"genre_scores_gemma":[0.9933403,0.0002568512,0.005823009,0.00001610286,0.00007399648,0.00009810535,0.0003228861,0.00002182075,0.00004698127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01653508,"threshold_uncertainty_score":0.8792571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03527429610955636,"score_gpt":0.3271415092778652,"score_spread":0.2918672131683088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}