{"id":"W2070121589","doi":"10.1592/phco.24.6.564.34743","title":"Tobramycin Pharmacokinetics in Children with Febrile Neutropenia Undergoing Stem Cell Transplantation: Once‐Daily versus Thrice‐Daily Administration","year":2004,"lang":"en","type":"article","venue":"Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy","topic":"Neutropenia and Cancer Infections","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Cancer Care Ontario; SickKids Foundation","funders":"Hospital for Sick Children","keywords":"Medicine; Tobramycin; Pharmacokinetics; Dosing; Cmax; Neutropenia; Population; Transplantation; Volume of distribution; Anesthesia; Loading dose; Febrile neutropenia; Confidence interval; Surgery; Internal medicine; Antibiotics; Chemotherapy; Gentamicin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005470127,0.0003395962,0.0004579631,0.0002418189,0.000362366,0.00004904121,0.0002605525,0.00007190093,0.0004168853],"category_scores_gemma":[5.893188e-7,0.0002298567,0.0001222064,0.0003436522,0.0002301363,0.0003652054,0.00001181709,0.0008055398,0.000005513682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001481474,"about_ca_system_score_gemma":0.0004373476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004204542,"about_ca_topic_score_gemma":0.00007074136,"domain_scores_codex":[0.9981087,0.0003366455,0.0006138294,0.0002492918,0.0003270395,0.0003645137],"domain_scores_gemma":[0.9988705,0.0001932434,0.0004557804,0.0001391507,0.000142817,0.0001985046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.04340762,0.001675575,0.02713514,0.00008221412,0.001301209,0.0002467905,0.006011275,0.003582702,0.9073097,0.0001266176,0.001869778,0.007251392],"study_design_scores_gemma":[0.1271732,0.007258208,0.03891397,0.0001351866,0.001366561,0.002664622,0.0007115953,0.00002001478,0.8178627,0.0001695401,0.003194671,0.0005296996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892547,0.005797172,0.0001486315,0.002865697,0.0005074426,0.0008268205,0.000009107303,0.00003474493,0.0005556748],"genre_scores_gemma":[0.9575236,0.0385416,0.0000897835,0.002938373,0.0006710985,0.00002752586,0.000006716956,0.00005320534,0.0001480419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08944698,"threshold_uncertainty_score":0.9373285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02070937334553578,"score_gpt":0.3188148475689536,"score_spread":0.2981054742234178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}