{"id":"W2070144977","doi":"10.1038/nm800","title":"An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections","year":2002,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":353,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Superantigen; Immunology; Pharyngitis; Disease; Haplotype; Biology; Immunogenetics; Allele; Toxic shock syndrome; Human leukocyte antigen; Streptococcus; Antigen; Medicine; Immune system; Staphylococcus aureus; Genetics; T cell; Gene; Internal medicine; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007808387,0.0001655159,0.0004682592,0.0002805617,0.00004527867,0.000004367962,0.0000453229,0.0002020244,0.0002283199],"category_scores_gemma":[0.0004190372,0.0001105642,0.00006982061,0.0003003321,0.0001573426,0.00004470743,0.00001360228,0.0002435534,0.000001056142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004043636,"about_ca_system_score_gemma":0.00001351572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002048296,"about_ca_topic_score_gemma":0.0001966914,"domain_scores_codex":[0.9991219,0.00003413408,0.0002760802,0.0002514112,0.0001516164,0.0001648813],"domain_scores_gemma":[0.999214,0.0002723832,0.00007407094,0.0002384373,0.00009102447,0.0001100981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003524021,0.0007384909,0.9766405,0.00007133673,0.0001688976,0.00001600675,0.0002638014,6.107082e-7,0.01657532,0.0004523571,0.00005529819,0.004982113],"study_design_scores_gemma":[0.004222864,0.003237898,0.9873201,0.000263314,0.0002634603,0.00003263169,0.0002284991,0.0001760842,0.003705253,0.0003205369,0.0001303415,0.00009898657],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950706,0.002283036,0.0001630427,0.0008995909,0.0001220255,0.0009756129,0.00001898048,0.00002520674,0.0004419193],"genre_scores_gemma":[0.9987397,0.0002361955,0.0004034613,0.0002623657,0.00005106076,0.0002151558,0.0000281851,0.0000137333,0.00005016034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01287007,"threshold_uncertainty_score":0.4508678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01913290504545571,"score_gpt":0.3068292973247959,"score_spread":0.2876963922793401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}