{"id":"W2070144977","doi":"10.1038/nm800","title":"An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections","year":2002,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":353,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Superantigen; Immunology; Pharyngitis; Disease; Haplotype; Biology; Immunogenetics; Allele; Toxic shock syndrome; Human leukocyte antigen; Streptococcus; Antigen; Medicine; Immune system; Staphylococcus aureus; Genetics; T cell; Gene; Internal medicine; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006500215,0.0002066107,0.0003892391,0.0005996852,0.0002678192,0.0007019024,0.0004525528,0.0006225019,0.002069488],"category_scores_gemma":[0.003211805,0.0001587429,0.0002969033,0.0005603087,0.0004602747,0.0003868638,0.0004305413,0.0008809453,0.0002918332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002275257,"about_ca_system_score_gemma":0.0003468557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006334241,"about_ca_topic_score_gemma":0.0003935675,"domain_scores_codex":[0.9993607,0.0002220909,0.00004767753,0.0001030386,0.00008689462,0.0001796951],"domain_scores_gemma":[0.9978904,0.0006427941,0.0006874174,0.0002615805,0.0001439793,0.0003738042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002871577,0.0004476575,0.9210148,0.00004053537,0.0002461294,0.0005347613,0.0004833214,0.0003738106,0.06177912,0.00105179,0.0003066371,0.01084976],"study_design_scores_gemma":[0.00002751375,0.0003307551,0.9963819,0.000006308019,0.00004732341,0.0004075567,0.0002090491,0.0002073339,0.00161319,0.000605396,0.0001569175,0.000006733563],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990712,0.0001733981,0.0001118934,0.00009742602,0.000009625346,0.000003970914,0.00008399497,0.000003069506,0.0004452863],"genre_scores_gemma":[0.9996207,0.00005940091,0.00004855647,0.0000401827,0.00001468849,0.000003505156,0.00008645468,0.000002529229,0.0001240221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002069488,"threshold_uncertainty_score":0.006923079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01913290504545571,"score_gpt":0.3068292973247959,"score_spread":0.2876963922793401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}