{"id":"W2070192115","doi":"10.1095/biolreprod67.1.301","title":"Regulation of the Human Sperm Tyrosine Kinase c-yes. Activation by Cyclic Adenosine 3′,5′-Monophosphate and Inhibition by Ca2+ 1","year":2002,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôpital Saint-François d'Assise","funders":"","keywords":"Biology; Tyrosine phosphorylation; Capacitation; Protein tyrosine phosphatase; Phosphorylation; Tyrosine; Tyrosine kinase; Proto-oncogene tyrosine-protein kinase Src; Protein kinase A; Sperm; Biochemistry; Kinase; Protein phosphorylation; Receptor tyrosine kinase; Cell biology; Signal transduction; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001719064,0.0001058508,0.0001886811,0.00006842396,0.00009079882,0.000003188223,0.00002394245,0.0001356068,0.00009594996],"category_scores_gemma":[0.0002269059,0.0000808784,0.000044563,0.000218839,0.0002355129,0.00009735255,0.00001752168,0.0000944312,0.000002440957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004567216,"about_ca_system_score_gemma":0.000006186871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001436953,"about_ca_topic_score_gemma":0.000001540948,"domain_scores_codex":[0.9991143,0.00005562462,0.0002858902,0.0003408402,0.0001054548,0.00009793614],"domain_scores_gemma":[0.9992089,0.00001640606,0.0002829174,0.0003331673,0.0001303768,0.00002826317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004786375,0.0001596256,0.02392169,0.00004476752,0.00001989013,1.082952e-7,0.00006596847,0.000002267682,0.9595505,0.0001598936,0.006185521,0.009841931],"study_design_scores_gemma":[0.0007365816,0.0003020876,0.1660189,0.00006272459,0.0000610608,0.00002553505,0.00002057054,0.00006579432,0.8288842,0.000223834,0.003534319,0.0000644206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930776,0.003662383,0.0001870674,0.002275551,0.0002329502,0.0003585943,0.00001002391,0.0000329248,0.0001629],"genre_scores_gemma":[0.9984123,0.0003080142,0.00009519551,0.00003685216,0.0001726374,0.000009302695,0.000228009,0.00001133674,0.0007264215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1420972,"threshold_uncertainty_score":0.3298125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01663722071284681,"score_gpt":0.2373294773997785,"score_spread":0.2206922566869317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}