{"id":"W2070192115","doi":"10.1095/biolreprod67.1.301","title":"Regulation of the Human Sperm Tyrosine Kinase c-yes. Activation by Cyclic Adenosine 3′,5′-Monophosphate and Inhibition by Ca2+ 1","year":2002,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôpital Saint-François d'Assise","funders":"","keywords":"Biology; Tyrosine phosphorylation; Capacitation; Protein tyrosine phosphatase; Phosphorylation; Tyrosine; Tyrosine kinase; Proto-oncogene tyrosine-protein kinase Src; Protein kinase A; Sperm; Biochemistry; Kinase; Protein phosphorylation; Receptor tyrosine kinase; Cell biology; Signal transduction; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009864563,0.000179257,0.000104733,0.0001310134,0.0001567441,0.0001629209,0.0001202543,0.0002135369,0.001159242],"category_scores_gemma":[0.0001130639,0.00008688017,0.000181292,0.00008405036,0.0001543163,0.0001103279,0.0001330974,0.0002025527,0.0002554437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000222425,"about_ca_system_score_gemma":0.0001267072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000791406,"about_ca_topic_score_gemma":0.001346115,"domain_scores_codex":[0.9999217,0.00001410135,0.000005835414,0.00001972996,0.00001762663,0.00002104731],"domain_scores_gemma":[0.999946,0.00001269687,0.00001542852,0.000003653985,0.00001170735,0.00001060394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001989642,0.0000138947,0.0003814799,0.00005621209,0.000004879407,0.00009507712,0.00002282182,0.00002268197,0.9975455,0.000107091,0.00005940198,0.001492055],"study_design_scores_gemma":[0.00003726523,0.0004974847,0.06644917,0.00001470821,0.000029325,0.0009265493,0.00008766576,0.001667114,0.9242642,0.000101076,0.005917332,0.000008097815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879906,0.008745387,0.001426537,0.0001828429,0.00003870587,0.00002969655,0.0002817906,0.00002720059,0.00127719],"genre_scores_gemma":[0.9946595,0.001902022,0.0007188321,0.00005693563,0.00001421441,0.00002963454,0.0004121645,0.000003195376,0.002203524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001159242,"threshold_uncertainty_score":0.003878057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01663722071284681,"score_gpt":0.2373294773997785,"score_spread":0.2206922566869317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}