{"id":"W2070310839","doi":"10.1002/hep.20073","title":"Effect of peginterferon alfa-2a on liver histology in chronic hepatitis C: A meta-analysis of individual patient data","year":2004,"lang":"en","type":"review","venue":"Hepatology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":227,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; University Health Network","funders":"","keywords":"Medicine; Internal medicine; Gastroenterology; Odds ratio; Body mass index; Randomized controlled trial; Hepatology; Fibrosis; Hepatitis C; Ribavirin; Alpha interferon; Histology; Overweight; Interferon alfa; Chronic hepatitis; Interferon; Immunology; Cancer; Immunotherapy; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001541082,0.0007623038,0.01335956,0.00360425,0.00002830393,0.000006989122,0.001262845,0.001017641,0.002333537],"category_scores_gemma":[0.0009563369,0.0005668464,0.002423506,0.001800131,0.0005621325,0.00006725887,0.0009522227,0.001277051,0.0001418918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001509365,"about_ca_system_score_gemma":0.002171224,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008546337,"about_ca_topic_score_gemma":0.01209137,"domain_scores_codex":[0.9915161,0.003252635,0.002208281,0.001343193,0.0009181855,0.0007615851],"domain_scores_gemma":[0.9935361,0.002027689,0.001149992,0.002938839,0.0001508348,0.0001966116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0002320898,0.000461561,0.003690486,0.03941055,0.1582536,0.001681288,0.0001868125,0.000008194823,9.63907e-7,0.0001654533,0.0007191639,0.7951899],"study_design_scores_gemma":[0.001275453,0.009693919,0.0001312288,0.002640174,0.5144317,0.0001801298,0.000001955264,0.0005509992,0.00004004141,0.000005026062,0.4705794,0.0004699328],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002855859,0.9921121,0.00001750094,0.00005799027,0.0001436775,0.002177258,0.002144135,0.0000236867,0.0004677676],"genre_scores_gemma":[0.04552796,0.9499228,0.00009538262,0.00005907335,0.00003044702,0.0003842734,0.003838646,0.00008687579,0.00005456037],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7947199,"threshold_uncertainty_score":0.9996783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.249801508376833,"score_gpt":0.4516413983123238,"score_spread":0.2018398899354908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}